Inpatient Management of Migraine

Marmura, Michael J.; Goldberg, Stephanie Wrobel

doi:10.1007/s11910-015-0539-z

Cited by 9 publications

(3 citation statements)

References 80 publications

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“…We performed separate analyses for outpatient migraine diagnoses only, as well as outpatient and inpatient diagnoses, together. By removing the inpatient diagnoses, individuals with the highest degree of psychiatric and somatic comorbidities, medication overuse and highest pain scores were excluded25 rendering the patient group more homogeneous. We also performed a separate set of analyses including only primary diagnoses of migraine.…”

Section: Methodsmentioning

confidence: 99%

Cardiovascular fitness and risk of migraine: a large, prospective population-based study of Swedish young adult men

Nyberg¹,

Gustavsson

Linde

et al. 2019

BMJ Open

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ObjectivesTo examine the longitudinal relationship between cardiovascular fitness in young adult men and future risk of migraine and to estimate eventual differential effects among categories of body mass index (BMI) and blood pressure.DesignNational, prospective, population-based cohort study.SettingSweden 1968–2014.Participants18-year-old Swedish men (n=1 819 828) who underwent mandatory military conscription examinations during the years 1968–2005.Primary and secondary outcomesThe primary outcome was the first dispensation of prescribed migraine-specific medication, identified using the Swedish Prescribed Drug Register. The secondary outcome was documented migraine diagnosis from the Swedish National Hospital Register.ResultsDuring follow-up, 22 533 men filled a prescription for migraine-specific medication. After confounding adjustment, compared with high cardiovascular fitness, low and medium fitness increased the risk of migraine-specific medication (risk ratio (RR)low: 1.29, 95% CI 1.24 to 1.35; population attributable fraction: 3.6%, 95% CI 1.7% to 5.3% and RRmedium: 1.15, 95% CI 1.12 to 1.19; population attributable fraction: 8.0%, 95% CI 4.0% to 11.7%). To assess potential effect measure modification, stratified analyses of these association by levels of BMI and blood pressure showed that lower fitness levels increased risk of migraine across all groups except among underweight men or men with high diastolic blood pressure.ConclusionsYoung men with a lower cardiovascular fitness had a higher long-term risk of developing pharmacological prescription-requiring migraine. This study contributes with information regarding risk factors for migraine in men, an understudied population in migraine research.

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Section: Methodsmentioning

confidence: 99%

Cardiovascular fitness and risk of migraine: a large, prospective population-based study of Swedish young adult men

Nyberg¹,

Gustavsson

Linde

et al. 2019

BMJ Open

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“…Though headache is treated on an outpatient basis and is one of the most common diagnoses in OPD neurology clinics, [ 10 ] migraine continues to be an important reason for inpatient admissions. Studies from Western countries like the USA have shown, 63% of admitted headaches were for treatment of migraine [ 11 ]. Similarly, in a district general hospital in England, 17.7% of neurology admissions were for headaches [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Inpatient Burden of Neurological Disorders: A Route Map for Allocation of Resources and Postgraduate Training

Dsouza,

John,

Nadig

et al. 2023

Cureus

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Introduction There are limited data regarding the profile of inpatient neurological disorders in India. Understanding the spectrum of diseases and the profile of patients admitted in an inpatient setting will help to streamline services, allocate resources, develop management protocols, design curricula, and improve training programs of postgraduate students in neurology training. Objective The objective of this study is to study the profile of inpatient neurological disorders in 1000 consecutive patients admitted to a tertiary care neurological center. Methods Data from 1000 consecutive inpatients admitted to the Neurology Department at St. John’s Medical College Hospital, Bengaluru from January 2018 to October 2018 were collected from the medical records. The data obtained from the case records were entered into a Microsoft Excel spreadsheet for descriptive analysis. Results The average age of the patients was 48 years (±18.18) and 606 of the 1000 patients were males. Strokes, including arterial and venous strokes, formed the major inpatient caseload, accounting for 48.7% of cases. Of these, 84% had ischemic arterial strokes, 7.4% had intracranial hemorrhage, and 8.4 % had cerebral sinus venous strokes; 19.3% of patients were admitted for seizures while 8.2% of patients were admitted for headache. Meningitis was diagnosed in 5.2% of patients; 4.8% of patients had central nervous system demyelinating and autoimmune diseases. A number of other diagnoses comprised less than 2.5% each and included movement disorders, peripheral nerve, spine and nerve roots disorders, neuromuscular diseases, neurodegenerative diseases, and medical and functional illness. Conclusion The most common disorders in the inpatient setting are stroke, seizure, headache, meningitis, and autoimmune/demyelinating disorders. These disorders should receive priority while planning the allocation of resources, educational curriculum, training, and teaching programs.

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“…To reduce the risk of posttreatment akathisia, diphenhydramine or benztropine may be given before starting a dopamine receptor antagonist. Diphenhydramine may be independently effective in migraine treatment, 6,7 but data on this are limited.…”

Section: ■ Options For Drug Therapymentioning

confidence: 99%