The influence of crop regulation on guava fruit quality (Psidium guajava) manifests in various dimensions, including physical appearance, nutritional integrity, yield, and overall productivity. This investigation explores the systematic integration of conventional and modern practices in regulating the characteristics of guava fruit. Physical appearance, including size, shape, color, and texture, is primarily influenced by targeted pruning and meticulous nutrient and water regulation. Nutritional content, encompassing essential vitamins, minerals, and antioxidants, can be enhanced and preserved through a combination of soil management, precision irrigation, and genetic engineering. Crop regulation's interplay with yield and productivity highlights the vital role of balanced pruning, efficient water and nutrient delivery systems, and modern techniques such as precision agriculture. A key finding reveals a complex challenge in maintaining a quality-quantity balance, necessitating innovation and sustainable practices for long-term benefits. This study underscores the multifaceted impacts of crop regulation on guava fruit quality and lays the groundwork for further research, emphasizing the development of integrated and sustainable strategies for optimizing both the quality and economic value of this globally significant fruit.