Insecticide Absorption from Indoor Surfaces

Berteau, Peter E.; Knaak, James B.; Mengle, Donald C.; Schreider, Jay

doi:10.1021/bk-1988-0382.ch024

Cited by 22 publications

(14 citation statements)

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“…Default assumptions used to calculate human exposure and absorbed daily dosage (ADD) from environmental measurements of air and surface residues typically overestimate measurements obtained through biomonitoring (Krieger et al, 2000). Published exposure estimates following the indoor use of foggers have been as high as 50 mg/kg/day (Berteau et al, 1989), while measurements of ADD following indoor pesticide use normally range from 1 to 10 mg/kg/day . The difference between predicted and measured ADD warrants the study of potential determinants of exposure and bioavailability.…”

Section: Introductionmentioning

confidence: 99%

Perspiration increased human pesticide absorption following surface contact during an indoor scripted activity program

Williams

Aston²,

Krieger

2004

J Expo Sci Environ Epidemiol

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Homeowners and professional applicators frequently use chemicals to control insect pests in urban environments. The identification and evaluation of determinants of human exposure are critical to conduct reliable and responsible human exposure assessments following indoor residential chemical applications. The effect of sweat on absorbed dose in humans was evaluated with human volunteers who participated in a structured activity program (SAP). Participants (n ¼ 20) performed a warm-up exercise to induce light sweating prior to an SAP on chlorpyrifos(cp)-treated nylon carpet. Absorbed daily dosages (ADDs) were calculated using urinary biomonitoring of trichloropyridinol. In two separate exposures, participation in the warm-up exercise prior to the exposure SAP resulted in an increased ADD of CP equivalents by approximately 50%. Measured ADDs averaged 2.8 (SAP 1) and 2.0 (SAP 2) mg CP equivalents/kg/day in volunteers who participated in the warm-up exercise. In participants who rested prior to the exposures, ADDs were significantly lower at 1.9 (SAP 1) and 1.3 (SAP 2) mg CP equivalents/kg/day. Perspiration may also be a determinant of exposure in active children and field workers. Measured ADDs were less than estimates of ADD made from environmental measurements including CP deposition, the California roller, and clothing dosimeters worn by participants.

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Section: Introductionmentioning

confidence: 99%

Perspiration increased human pesticide absorption following surface contact during an indoor scripted activity program

Williams

Aston²,

Krieger

2004

J Expo Sci Environ Epidemiol

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“…Many different methods have been used to assess dermal exposure to chemicals, but rarely have these included the use of biological markers of exposure (biomonitoring) to determine actual absorbed dosage (AD ). As a result, default assumptions are used that often inflate exposure estimates of AD ( e.g., Berteau et al, 1989 ) and may mislead risk managers who must assess chemical exposures and develop mitigation strategies. Default estimates may also be the basis of incompletely researched media coverage and casual technical evaluation that prompts unwarranted public alarm and misunderstanding of science and the regulatory process.…”

Section: Introductionmentioning

confidence: 99%

Biomonitoring and whole body cotton dosimetry to estimate potential human dermal exposure to semivolatile chemicals

Krieger

Bernard

Dinoff

et al. 2000

J Expo Sci Environ Epidemiol

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Current methods of estimating absorbed dosage ( AD ) of chemicals were evaluated to determine residue transfer from a carpet treated with chlorpyrifos (CP) to humans who performed a structured exercise routine. To determine the dislodgeability of residue, a California Department of Food and Agriculture ( CDFA ) roller was applied to a flat cotton cloth upon a treated carpet. Levels ranged from 0.06 to 0.99 g CP/cm 2 . Cotton whole body dosimeters ( WBD ) were also used to assess residue transfer. The dosimeters retained 1.5 to 38 mg CP / person. Urine biomonitoring ( 3 days ) for 3,5,6 -trichloro -2 -pyridinol ( TCP ) of persons who wore only swimsuits revealed a mean AD of 176 g CP equivalents / person. The results show that the AD depends on the extent of contact transfer and dermal absorption of the residue. Default exposure assessments based upon environmental levels of chemicals and hypothetical transport pathways predict excessive exposure. The cotton WBD retains chemical residues and may be effectively used to predict dermal dose under experimental conditions.

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“…In Jacksonville, chlorpyrifos was found in 100% ofthe household indoor air (1. In addition to indoor air, insecticides can be found on floors and other surfaces and may contribute significantly to the total exposure of the general population. However, there is a paucity of data available for making an accurate assessment of the relative importance of oral (nondietary), dermal, and inhalation exposures to household pesticides (8)(9)(10) (15).…”

mentioning

confidence: 99%

Accumulation of Chlorpyrifos on Residential Surfaces and Toys Accessible to Children

Gurunathan¹,

Freeman²,

Buckley³

et al. 1998

Environmental Health Perspectives

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Insecticide Absorption from Indoor Surfaces

Cited by 22 publications

References 0 publications

Perspiration increased human pesticide absorption following surface contact during an indoor scripted activity program

Perspiration increased human pesticide absorption following surface contact during an indoor scripted activity program

Biomonitoring and whole body cotton dosimetry to estimate potential human dermal exposure to semivolatile chemicals

Accumulation of Chlorpyrifos on Residential Surfaces and Toys Accessible to Children

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