Insectivores (Hedgehogs, Moles, and Tenrecs)

Heard, Darryl J.

doi:10.1002/9781118792919.ch33

Cited by 2 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9 12 18 One animal vomited shortly ater the intramuscular administration and this may likely be a side efect of dexmedetomidine; α-2 agonists are reported to cause vomiting but fasting, as a preventive treatment, is avoided in this species because it may predispose to hypoglycaemia. 6 In conclusion, the combination of dexmedetomidine and alfaxalone may represent a feasible combination to restrain European hedgehogs and it allowed to perform non-painful procedures that lasted 20-25 minutes. In heavy animals an additional dose may be required to achieve adequate immobilisation.…”

Section: Discussionmentioning

confidence: 93%

“…7 9 The PR measured ater the loss of the RiRef is considered lower than those usually reported in the non-hibernating hedgehog. 6 Medetomidine and its active enantiomer dexmedetomidine cause bradycardia and this is demonstrated in several species, including rats, rabbit and hedgehogs. 4 7-9 Atipamezole at the doses used was adequate to antagonise the α-2 agonistsmediated bradycardia.…”

Section: Discussionmentioning

confidence: 99%

“…Inhalant anaesthetics have been used to immobilise diferent small wildlife mammals and laboratory rodents although they present with some disadvantages. [3][4][5][6] The lack of adequate anaesthetic equipment in those species may not allow to safely secure the airways and minimise the anaesthetic pollution of the working environment, exposing staf to the volatile agents. Moreover, in an outdoor clinical situation, an anaesthetic machine may not be available.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of alfaxalone and dexmedetomidine for intramuscular restraint in European hedgehogs (Erinaceus europaeus)

et al. 2019

View full text Add to dashboard Cite

The European hedgehogs may require the use of chemical restraint for clinical examination because of their tendency to roll up as a defensive behaviour. This study evaluated the effects of alfaxalone combined with dexmedetomidine for restraint of hedgehogs undergoing pre-release health checks and atipamezole for recovery.Twenty hedgehogs received alfaxalone 2 mg/kg and dexmedetomidine 0.05 mg/kg intramuscularly in the quadriceps. If the righting reflex was still present, both drugs were administered at half of the initial doses. A semiquantitative scale scored sedation; clinical variables evaluated included pulse rate, respiratory rate, arterial haemoglobin oxygen saturation, end-tidal CO2 and body temperature.The righting reflex disappeared between 141 and 880 seconds. Overweight animals required one additional injection to achieve adequate relaxation. Pulse rate decreased during the procedure and increased after atipamezole administration. Respiratory rate and end-tidal CO2 did not change statistically throughout the procedure but one hedgehog showed haemoglobin oxygen saturation lower than 90%. Recovery after atipamezole was smooth and complete. Body temperature decreased over time.The sedation protocol may represent an effective combination to restrain European hedgehogs and atipamezole provides a rapid antagonism. Additional sedatives administration may be required in overweight animals and an external source of oxygen should be available.

show abstract

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of alfaxalone and dexmedetomidine for intramuscular restraint in European hedgehogs (Erinaceus europaeus)

et al. 2019

View full text Add to dashboard Cite

show abstract

Evaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris)

Hawkins¹,

Doss²,

Mans³

2020

javma

View full text Add to dashboard Cite

OBJECTIVE To evaluate SC administration of 2 sedation protocols, ketamine-midazolam (KM) and alfaxalone-midazolam (AM), in African pygmy hedgehogs (Atelerix albiventris). ANIMALS 9 healthy adult hedgehogs (5 males, 4 females). PROCEDURES A randomized, blinded, complete crossover study was performed. Sedation was induced by SC administration of either ketamine (30 mg/kg [14 mg/lb]) with midazolam (1 mg/kg [0.45 mg/lb]) or alfaxalone (3 mg/kg [1.4 mg/lb]) with midazolam (1 mg/kg), including a 2-week washout period between treatments. Flumazenil (0.05 mg/kg [0.02 mg/lb], SC) was administered 45 minutes after administration of either protocol to reverse the effects of midazolam. Physiologic variables, reflexes, and behaviors were monitored. Food intake and body weight were measured before and after sedation. RESULTS Deep sedation characterized by complete loss of the righting reflex, decreased jaw tone, decreased pelvic limb withdrawal reflex, and preservation of the palpebral reflex was produced in 7 of 9 hedgehogs after KM administration and all 9 hedgehogs after AM administration. Mean ± SD time to loss of righting reflex was 6.4 ± 2.4 minutes after KM administration and 10 ± 4.0 minutes after AM administration. Following flumazenil administration, no significant difference was found in recovery time between sedation with KM (18.8 ± 12.7 minutes) and AM (14.4 ± 7.8 minutes). No significant differences were found in respiratory rate, oxygen saturation, or body temperature between protocols, whereas heart rate was higher for sedation with KM. Both sedation protocols resulted in a transient reduction in food intake. CONCLUSIONS AND CLINICAL RELEVANCE Subcutaneous administration of KM and AM provided deep sedation that might be useful to facilitate routine, noninvasive procedures in hedgehogs.

show abstract

Insectivores (Hedgehogs, Moles, and Tenrecs)

Cited by 2 publications

References 11 publications

Evaluation of alfaxalone and dexmedetomidine for intramuscular restraint in European hedgehogs (Erinaceus europaeus)

Evaluation of alfaxalone and dexmedetomidine for intramuscular restraint in European hedgehogs (Erinaceus europaeus)

Evaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris)

Contact Info

Product

Resources

About