Inside Cover: Fabrication of Layer‐by‐Layer Assembled Biomimetic Nanochannels for Highly Sensitive Acetylcholine Sensing (Chem. Eur. J. 24/2013)

Abstract

Inspired by the role of acetylcholine… … in biological channels, biomimetic nanochannels were prepared in PET polymer films. The channel surface was modified with p-sulfonatocalix[4]arene (SCX4) by flexible layer-by-layer electrostatic assembly. The presence of acetylcholine (Ach) caused the occurrence of host-guest inclusion between SCX4 and Ach on the inner wall. Even at low concentrations of Ach (1 nm), there was an obvious change in the rectified ionic flux. For more details, see the Communication by H. Li et al. on page 7686 ff.