Insight and schizophrenia

Buckley, Peter F.; Hasan, Samia; Friedman, Lee; Cerny, Cathleen A.

doi:10.1053/comp.2001.16569

Cited by 54 publications

(23 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On cross-sectional analyses, lack of insight has been closely linked to poor global functioning [24][25][26], and poor treatment compliance [27,28]. Lack of insight has also been closely associated with severe psychopathology [4,15,29], although inverse or no direct relationships have also been reported [8,16,30] Similarly, a number of studies have reported an inverse [31][32][33] but also positive [34][35][36] relationship between insight and positive symptoms, suggesting therefore that insight may be largely independent of psychopathology severity [37,38] as such, recent research interest has now been shifted onto specific symptom dimensions. For instance, weak to modest relationships have been reported between insight and anxiety [23,39,40] or depressive symptomatology [32,41,42].…”

Section: Introductionmentioning

confidence: 99%

Insight, Global Functioning and Psychopathology Amongst In-patient Clients with Schizophrenia

Stefanopoulou

Lafuente²,

Fonseca³

et al. 2009

Psychiatr Q

View full text Add to dashboard Cite

To explore whether cognitive impairment and global functioning can predict the degree of insight into illness as well as whether insight is mediated by specific symptom dimensions of psychopathology in schizophrenia. A dimensional/cross sectional approach was used. A mixed group of clients (n = 36) were assessed as part of a routine clinical evaluation. The Wechsler Adult Intelligence Scale (WAIS) was used as a measure of intellectual performance, the Brief Symptom Inventory (BSI) was used as a measure of general psychopathology while the Global Assessment of Functioning (GAF) scale assessed clients' psychosocial functioning; insight was assessed with the Insight and Treatment Attitudes Questionnaire (ITAQ). The correlation matrix of all outcome variables was examined; confounding effects of illness duration were tested by partial correlation analyses. GAF correlated with insight (rho = 0.41, P = 0.01) and the interpersonal sensitivity dimension of BSI (rho = -0.38, P = 0.03. Insight correlated positively with the anxiety (rho = 0.38, P = 0.03) and psychoticism (rho = 0.36, P = 0.04) dimensions of BSI. Our results suggest that insight is part of the phenomenology in schizophrenia, not being determined by neurocognitive disturbances. Improved insight was associated with more frequent psychotic symptoms endorsement, higher levels of anxiety and less severe psychopathological symptoms and difficulties in psychosocial functioning; clients with more pronounced difficulties in their personal and social interactions exhibited worse psychosocial functioning and more severe psychopathological symptoms.

show abstract

Section: Introductionmentioning

confidence: 99%

Insight, Global Functioning and Psychopathology Amongst In-patient Clients with Schizophrenia

Stefanopoulou

Lafuente²,

Fonseca³

et al. 2009

Psychiatr Q

View full text Add to dashboard Cite

show abstract

“…There have been numerous double-blind trials comparing the efficacy and tolerability of SGAs with FGAs for acute and maintenance therapy in schizophrenia (Miyamoto et al 2003;Buckley et al 2001;Leucht et al 2003), the results suggest that SGAs are at least as effective as FGAs in alleviating positive symptoms of psychosis.…”

Section: The Potential Benefits Of Antipsychoticsmentioning

confidence: 99%

Antipsychotics in the treatment of psychosis: risks and benefits

Mutsatsa

Bressington

2013

British Journal of Mental Health Nursing

View full text Add to dashboard Cite

BoxAntipsychotics are important in the treatment and recovery of people with psychosis but current evidence suggests that mental health nurses are not always conversant with the risks and benefits of these drugs. This inadequate knowledge has important ramifications for the provision of safe and effective medication management. This article outlines the utility and safety considerations associated with the different groups of antipsychotic drugs currently available in order that ……….

show abstract

“…Neuropsychological deficits have been studied as the basis for poor insight in the past 2 decades [14,15,16,17,18]. In fact, DSM-IV-TR includes a lack of insight as one of the associated features of schizophrenia, and states: ‘A majority of individuals with schizophrenia have poor insight regarding the fact that they have a psychotic illness.…”

Section: Introductionmentioning

confidence: 99%

“…Amador and David [20] proposed that poor insight that is severe, persistent, insensitive to logic or evidence and is associated with cognitive deficits, be labeled as anosognosia of the mental illness, like in certain neurological disorders. Although some studies have not found a relationship between neuropsychological deficits and different dimensions of insight [14,15], meta-analytical data suggest the opposite. Thus, the meta-analysis carried out by Aleman et al [21] found insight to be associated with executive function [as measured using tests such as the Wisconsin Card-Sorting Test (WCST) and the Trail-Making Test (TMT)] as well as with general cognitive functioning, with small to medium effect sizes.…”

Section: Introductionmentioning

confidence: 99%

Differential Relationships between Set-Shifting Abilities and Dimensions of Insight in Schizophrenia

et al. 2013

View full text Add to dashboard Cite

Background: To assess insight in a large sample of patients with schizophrenia and to study its relationship with set shifting as an executive function. Methods: The insight of a sample of 161 clinically stable, community-dwelling patients with schizophrenia was evaluated by means of the Scale to Assess Unawareness of Mental Disorder (SUMD). Set shifting was measured using the Trail-Making Test time required to complete part B minus the time required to complete part A (TMT B-A). Linear regression analyses were performed to investigate the relationships of TMT B-A with different dimensions of general insight. Results: Regression analyses revealed a significant association between TMT B-A and two of the SUMD general components: ‘awareness of mental disorder' and ‘awareness of the efficacy of treatment'. The ‘awareness of social consequences' component was not significantly associated with set shifting. Conclusions: Our results show a significant relation between set shifting and insight, but not in the same manner for the different components of the SUMD general score.

show abstract

Insight and schizophrenia

Cited by 54 publications

References 17 publications

Insight, Global Functioning and Psychopathology Amongst In-patient Clients with Schizophrenia

Insight, Global Functioning and Psychopathology Amongst In-patient Clients with Schizophrenia

Antipsychotics in the treatment of psychosis: risks and benefits

Differential Relationships between Set-Shifting Abilities and Dimensions of Insight in Schizophrenia

Contact Info

Product

Resources

About