Insight into delivery of dermal fibroblast by non-biodegradable bacterial nanocellulose composite hydrogel on wound healing

Loh, Evelyn Yun Xi; Fauzi, Mh Busra; Ng, Min Hwei; Ng, Pei Yuen; Ng, Shiow Fern; Amin, Mohd Cairul Iqbal Mohd

doi:10.1016/j.ijbiomac.2020.05.011

Cited by 24 publications

(10 citation statements)

References 46 publications

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“…Stability in biological media over time is an essential requirement that has yet to be widely demonstrated with hydrogelbased devices. A possible strategy to address this challenge is to use synthetic monomers to further increase the lifetime of the structure (Takeda et al, 2015;Loh et al, 2020). In general, however, beside isolated examples, developing robust and standardized manufacturing methods accessible to the wider bioelectronic microfabrication community has yet to be achieved to unlock reproducible manufacturability of hydrogels at the microscale.…”

Section: Discussionmentioning

confidence: 99%

Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook

Saghir

Imenes

Schiavone

2023

Front. Bioeng. Biotechnol.

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Recent research aiming at the development of electroceuticals for the treatment of medical conditions such as degenerative diseases, cardiac arrhythmia and chronic pain, has given rise to microfabricated implanted bioelectronic devices capable of interacting with host biological tissues in synergistic modalities. Owing to their multimodal affinity to biological tissues, hydrogels have emerged as promising interface materials for bioelectronic devices. Here, we review the state-of-the-art and forefront in the techniques used by research groups for the integration of hydrogels into the microfabrication processes of bioelectronic devices, and present the manufacturability challenges to unlock their further clinical deployment.

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Section: Discussionmentioning

confidence: 99%

Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook

Saghir

Imenes

Schiavone

2023

Front. Bioeng. Biotechnol.

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“…The results showed that hydrogel had good properties. Thus, it is beneficial to wound healing and can be used as a wound dressing and cell carrier [92]. To solve the problems of bacterial infection and uncontrollable bleeding during wound healing, Liu et al designed a green nanocomposite hydrogel, which is a noncovalent (dynamic ionic bridge) cross-linked hydrogel, by introducing aminated silver nanoparticles (Ag-NH 2 NPs) and gelatin (G) into carboxylated cellulose nanofibers (CNF).…”

Section: Fibrinmentioning

confidence: 99%

Application of Nanomaterial in Hydrogels Related to Wound Healing

Liu

Song

Liu

et al. 2022

Journal of Nanomaterials

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Traditional dressings used for wound repair, such as gauze, have shortcomings; for example, they cannot provide a suitable microenvironment for wound recovery. Therefore, it is necessary to find a better dressing to overcome shortcomings. Hydrogel provides a suitable wet environment, has good biocompatibility, and has a strong swelling rate to absorb exudate. Nanomaterial in hydrogels has been used to improve their performance and overcome the shortcomings of current hydrogel dressings. Hydrogel dressing can also be loaded with nanodrug particles to exert a better therapeutic effect than conventional drugs and to make the dressing more practical. This article reviews the application of nanotechnology in hydrogels related to wound healing and discusses the application prospects of nanohydrogels. After searching for hydrogel articles related to wound healing, we found that nanomaterial can not only enhance the mechanical strength, antibacterial properties, and adhesion of hydrogels but also achieve sustained drug release. From the perspective of clinical application, these characteristics are significant for wound healing. The combination of nanomaterial and hydrogel is an ideal dressing with broad application prospects for wound healing in the future.

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“…Another division assumes hydrogels' biodegradation ability. The polysaccharide-based or protein-based hydrogels are biodegradable, while acrylatebased hydrogels belong to non-biodegradable hydrogels [87,88]. One of the most common hydrogel classifications is crosslinking methods that might occur either chemically or physically.…”

Section: Hydrogels Dedicated To the Tissue Engineering Applicationsmentioning

confidence: 99%

Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering

2021

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Injuries of the bone/cartilage and central nervous system are still a serious socio-economic problem. They are an effect of diversified, difficult-to-access tissue structures as well as complex regeneration mechanisms. Currently, commercially available materials partially solve this problem, but they do not fulfill all of the bone/cartilage and neural tissue engineering requirements such as mechanical properties, biochemical cues or adequate biodegradation. There are still many things to do to provide complete restoration of injured tissues. Recent reports in bone/cartilage and neural tissue engineering give high hopes in designing scaffolds for complete tissue regeneration. This review thoroughly discusses the advantages and disadvantages of currently available commercial scaffolds and sheds new light on the designing of novel polymeric scaffolds composed of hydrogels, electrospun nanofibers, or hydrogels loaded with nano-additives.

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Insight into delivery of dermal fibroblast by non-biodegradable bacterial nanocellulose composite hydrogel on wound healing

Cited by 24 publications

References 46 publications

Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook

Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook

Application of Nanomaterial in Hydrogels Related to Wound Healing

Hydrogel, Electrospun and Composite Materials for Bone/Cartilage and Neural Tissue Engineering

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