Insights into hookworm prevalence in Asia: a systematic review and meta-analysis

Zibaei, Mohammad; Nosrati, Mohammad; Shadnoosh, Farnosh; Houshmand, Elham; Karami, Maryam Fasihi; Rafsanjani, Mandana Khorsandi; Majidiani, Hamidreza; Ghaffarifar, Fatemeh; Cortes, Hélder; Dalvand, Sahar; Badri, Milad

doi:10.1093/trstmh/trz115

Cited by 34 publications

(18 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…From the eligible studies of this review, seven of them were used to estimate the pooled magnitude of intestinal helminthic infection from Ascaris lumbricoides 25% (95% CI 15-35%). This result is in agreement with a report of systematic review from Asia [70] is higher than a global prevalence of Ascaris lumbricoides 17% [95% CI 13-21%] [72] and a study conducted in Bangladesh 23% [73]. This variation could be attributable to the poor performance of water and sanitation program and inadequate health education service at the community level in Ethiopia.…”

Section: Discussionsupporting

confidence: 92%

“…This result is in agreement with a systematic review and meta-analysis in Nigeria [69]. However, this finding is higher than the finding of a systematic review and meta-analysis carried out in Asia [70] and Ethiopia [71]. Despite the differences in the pooled magnitude of hookworm infection, Ethiopia has to better practice hookworm infection controlling strategies in place.…”

Section: Discussionsupporting

confidence: 86%

See 1 more Smart Citation

Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

Boltena

El‐Khatib

Kebede

et al. 2021

IJERPH

View full text Add to dashboard Cite

Background: Coinfection of malaria and intestinal helminths affects one third of the global population, largely among communities with severe poverty. The spread of these parasitic infections overlays in several epidemiological locations and the host shows different outcomes. This systematic review and meta-analysis determine the pooled prevalence of malaria and intestinal helminthiases coinfections among malaria suspected patients in Ethiopia. Methods: Primary studies published in English language were retrieved using appropriate search terms on Google Scholar, PubMed/MEDLINE, CINHAL, Scopus, and Embase. The Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. A pooled statistical meta-analysis was conducted using STATA Version 14.0 software. The heterogeneity and publication bias were assessed using the I2 statistics and Egger’s test, respectively. Duval and Tweedie’s nonparametric trim and fill analysis using the random-effect analysis. The Random effects model was used to estimate the summary prevalence of comorbidity of malaria and soil transmitted helminthiases and the corresponding 95% confidence intervals (CI). The review protocol has registered in PROSPERO number CRD42019144803. Results: We identified ten studies (n = 6633 participants) in this study. The overall pooled result showed 13% of the ambulatory patients infected by malaria and intestinal helminths concurrently in Ethiopia. The pooled prevalence of Plasmodium falciparum and Plasmodium vivax, and mixed infections were 12, 30, and 6%, respectively. The most common intestinal helminth parasites detected were Hookworm, Ascaris lumbricoides, and Tirchuris trichiura. Conclusions: The comorbidity of malaria and intestinal helminths causes lower hemoglobin level leading to maternal anemia, preterm delivery, and still birth in pregnant women and lactating mother. School-aged children and neonates coinfected by plasmodium species and soil transmitted helminths develop cognitive impairment, protein energy malnutrition, low birth weight, small for gestational age, and gross motor delay. The Ministry of Health of Ethiopia and its international partners working on malaria elimination programs should give more emphasis to the effect of the interface of malaria and soil transmitted helminths, which calls for an integrated disease control and prevention.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 86%

Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

Boltena

El‐Khatib

Kebede

et al. 2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…Based on the phylogenetic tree, the sequences of A. ceylanicum from humans (MK792828-29), dogs (MK792824), and cats (MK792825) in Malaysia belong to the same haplotype MA02, confirming that transmission from dogs to humans has occurred. This species was also found in wildlife, such as Asian golden cat, leopard cat, civet, and wild canids [9,54,55]. The biological, epidemiological, and pathophysiological characteristics of A. ceylanicum in humans and other wildlife species in Thailand and their genetic diversity with isolates from companion animals deserve further investigation.…”

Section: Discussionmentioning

confidence: 93%

“…Common species of hookworm infection in dogs include Ancylostoma caninum, A. ceylanicum, A. braziliense, and Uncinaria stenocephala, while A. braziliense, A. tubaeforme, A. ceylanicum, and U. stenocephala are commonly found in cats [6,7]. Recent studies have shown that ancylostomiasis in humans results from Necator americanus, A. duodenale, and A. ceylanicum [5,8,9]. Among Ancylostoma species, A. ceylanicum is the only species of animal hookworms known to produce patent infections in humans and is an important cause of zoonotic ancylostomiasis in Asia and Southeast Asia [9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

“…Recent studies have shown that ancylostomiasis in humans results from Necator americanus, A. duodenale, and A. ceylanicum [5,8,9]. Among Ancylostoma species, A. ceylanicum is the only species of animal hookworms known to produce patent infections in humans and is an important cause of zoonotic ancylostomiasis in Asia and Southeast Asia [9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ancylostoma ceylanicum: The Neglected Zoonotic Parasite of Community Dogs in Thailand and Its Genetic Diversity among Asian Countries

Kladkempetch

Tangtrongsup

Tiwananthagorn

2020

Animals

View full text Add to dashboard Cite

Ancylostoma ceylanicum is a zoonotic helminth that is commonly found in domestic dogs and cats throughout Asia but is largely neglected in many countries. This study aimed to confirm the species of hookworm in dogs and soil environments and investigate the evolutionary analyses of A. ceylanicum among Thai and Asian populations. In a total of 299 dog fecal samples and 212 soil samples from 53 temples, the prevalence rates of hookworm infection by microscopic examination were 26.4% (79/299) and 10.4% (22/212) in dog and soil samples, respectively. A PCR-RFLP targeting the ITS region was then utilized to identify the hookworm species. In dogs, A. ceylanicum was the main hookworm species, and the rates of A. ceylanicum and A. caninum infections were 96.6% and 3.5%, respectively. The genetic characterization and diversity indices of the A. ceylanicumcox1 gene among Thai and Asian populations were evaluated. Nine haplotypes were identified from Thai A. ceylanicum, in which the haplotype diversity and the nucleotide diversity were 0.4436 and 0.0036, respectively. The highest nucleotide diversity of Chinese A. ceylanicum populations suggested that it could be the ancestor of the populations. Pairwise fixation indices indicated that Thai A. ceylanicum was closely related to the Malaysian population, suggesting a gene flow between these populations. The temples with hookworm-positive dogs were associated with the presence of hookworm-contaminated soil, as these levels showed an approximately four-fold increase compared with those in temples with hookworm-negative dogs (OR = 4.38, 95% CI: 1.55–12.37). Interestingly, the genotypes of A. ceylanicum in the contaminating soil and infecting dogs were identical. Therefore, increased awareness and concern from the wider public communities with regard to the responsibility of temples and municipal offices to provide proper deworming programs to community dogs should be strongly endorsed to reduce the risk of the transmission of this zoonotic disease. In addition, parasitic examination and treatment should be strongly implemented before dogs are imported and exported worldwide.

show abstract

Global prevalence of Trichomonas vaginalis among female sex workers: a systematic review and meta-analysis

et al. 2021

View full text Add to dashboard Cite

Trichomoniasis is a sexually transmitted infection (STI), caused by the protozoan parasite, Trichomonas vaginalis. Female sex workers are intensely affected by the infection, since they have frequent direct physical contact. The current systematic review and meta-analysis represents the global prevalence of T. vaginalis in female sex workers. Five databases (Science Direct, Scopus, PubMed, Web of Science, and Google Scholar) were explored for literatures that published from July 1985 to June 2020. Totally, 85 studies (54,515 participants) from 46 countries met the inclusion criteria. The global pooled prevalence of T. vaginalis was 16% (95% CI 13-19%). The estimated pooled prevalence based on methods including wet mount, culture, and molecular techniques was 15% (95% CI 12-19%), 16% (95% CI 10-24%), and 22% (95% CI 13-32%), respectively. Moreover, the infection was most prevalent at the mean age of 30-36 (20%, 95% CI 11-30%). Regarding the World Health Organization (WHO) regions, the highest pooled prevalence was estimated to be in the African region (23%, 95% CI 7-46%). In addition, we indicated that countries with low-income level have the highest pooled prevalence (23%, 95% CI 14-34%). Our results revealed that the worldwide prevalence of T. vaginalis was significant in female sex workers. Therefore, considering a precise strategy such as a health education program with regard to safe intercourse is needed to increase knowledge and prevent T. vaginalis infection in sex workers.

show abstract

Insights into hookworm prevalence in Asia: a systematic review and meta-analysis

Cited by 34 publications

References 47 publications

Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

Comorbidity of Geo-Helminthes among Malaria Outpatients of the Health Facilities in Ethiopia: Systematic Review and Meta-Analysis

Ancylostoma ceylanicum: The Neglected Zoonotic Parasite of Community Dogs in Thailand and Its Genetic Diversity among Asian Countries

Global prevalence of Trichomonas vaginalis among female sex workers: a systematic review and meta-analysis

Contact Info

Product

Resources

About