Insights into Insect Resistance in Pulse Crops: Problems and Preventions

Santisree, Parankusam; Katamreddy, Sricindhuri; Bommineni, Pradeep Reddy; Bhatnagar‐Mathur, Pooja; Sharma, Kiran K.

doi:10.1007/978-3-030-01743-9_7

Cited by 2 publications

(1 citation statement)

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“…Aphis craccivora, also identified as the cowpea aphid, is among the most threatening crop pests causing direct damage to plants by distorting and delaying plant growth. , The molasses produced by the vector are applied on the plant and encourage mold growth with soot limiting photosynthesis . It hosts many plants such as Rosaceae, Malvaceae, Asteraceae, Caryophyllaceae, Solanaceae, Chenopodiaceae, and Ranunculaceae families, but it appears to prefer groups of the bean family. − Aphids are vectors for a number of plant viruses such as mosaic virus, mottle virus, alfalfa mosaic virus, and peanut virus. , …”

Section: Introductionmentioning

confidence: 99%

Green Design, Synthesis, and Molecular Docking Study of Novel Quinoxaline Derivatives with Insecticidal Potential against Aphis craccivora

et al. 2022

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An efficient and environmentally friendly method was established for designing novel 3-amino-1,4-dihydroquinoxaline-2-carbonitrile ( 1 ) via the reaction of bromomalononitrile and benzene-1,2-diamine under microwave irradiation in an excellent yield (93%). This targeted amino derivative was utilized for the construction of a series of Schiff bases ( 8 – 13 ). A new series of thiazolidinone derivatives ( 15 – 20 ) were synthesized in high yields (89–96%) via treatment of thioglycolic acid with Schiff bases ( 8 – 13 ) under microwave irradiation in high yields (89–96%). Moreover, new pyrimidine derivatives ( 26 – 30 and 35 – 38 ) were prepared by treatment of compound 1 with arylidenes ( 21 – 25 ) and/or alkylidenemalononitriles ( 31 – 34 ) using piperidine as a basic catalyst under microwave conditions. Based on elemental analyses and spectral data, the structures of the new assembled compounds were determined. The newly synthesized quinoxaline derivatives were screened and studied as an insecticidal agent against Aphis craccivora . The obtained results indicate that compound 16 is the most toxicological agent against nymphs of cowpea aphids ( Aphis craccivora ) compared to the other synthesized pyrimidine and thiazolidinone derivatives. The molecular docking study of the new quinoxaline derivatives registered that compound 16 had the highest binding score (−10.54 kcal/mol) and the thiazolidinone moiety formed hydrogen bonds with Trp143.

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