Phys. Chem. Chem. Phys.
 2024
DOI: 10.1039/d3cp06006c
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Insights into the baicalein-induced destabilization of LS-shaped Aβ42 protofibrils using computer simulations

Gagandeep Kaur,
Opinder Kaur Mankoo,
Anupamjeet Kaur
et al.

Abstract: Amyloid-β (Aβ) peptide aggregates spontaneously into various aggregating species comprising oligomers, protofibrils, and mature fibrils in Alzheimer’s disease (AD). Disrupting β-sheet rich neurotoxic smaller soluble Aβ42 oligomers formed during early...

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