2013
DOI: 10.1002/ceat.201200718
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Insights into the Evaporation Kinetics of Indomethacin Solutions

Abstract: Evaporation rates play a key role in evaporation crystallization and the drying of crystal products. Raman analysis was used to study the effect of the evaporation rate on the polymorphs of indomethacin at room temperature. The studied solvents were highly volatile ethanol, acetone, and ethyl acetate. The approach was based on a mass transfer model of evaporation, and experimental flux measurements were used for model evaluation. Evaporation rates from porous carriers were also investigated. The studied mesopo… Show more

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Cited by 5 publications
(1 citation statement)
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“…In chemical industry, the crystal size distribution (CSD) of crystalline, powder, or granular products significantly influences the efficiency of downstream processes [1,2], bioavailability of active pharmaceutical ingredients [3][4][5][6], catalytic activity [7][8][9][10], and so on. Therefore, it is essential for CSD to be obtained online in manufacturing processes.…”
Section: Introductionmentioning
confidence: 99%
“…In chemical industry, the crystal size distribution (CSD) of crystalline, powder, or granular products significantly influences the efficiency of downstream processes [1,2], bioavailability of active pharmaceutical ingredients [3][4][5][6], catalytic activity [7][8][9][10], and so on. Therefore, it is essential for CSD to be obtained online in manufacturing processes.…”
Section: Introductionmentioning
confidence: 99%