2014
DOI: 10.1016/j.sjbs.2014.01.005
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Insights into the molecular mechanism of glucose metabolism regulation under stress in chicken skeletal muscle tissues

Abstract: As substantial progress has been achieved in modern poultry production with large-scale and intensive feeding and farming in recent years, stress becomes a vital factor affecting chicken growth, development, and production yield, especially the quality and quantity of skeletal muscle mass. The review was aimed to outline and understand the stress-related genetic regulatory mechanism, which significantly affects glucose metabolism regulation in chicken skeletal muscle tissues. Progress in current studies was su… Show more

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Cited by 12 publications
(8 citation statements)
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“…The KCNJ11 gene, found to be 2217 base pairs upstream of the aforementioned significant CNV segment, is known to regulate insulin secretion [56]. A glucose metabolism disorder is usually linked as a cause of reduced development of chicken muscle tissue under stress, especially in broilers [57]. This gene was enriched [58].…”
Section: Discussionmentioning
confidence: 99%
“…The KCNJ11 gene, found to be 2217 base pairs upstream of the aforementioned significant CNV segment, is known to regulate insulin secretion [56]. A glucose metabolism disorder is usually linked as a cause of reduced development of chicken muscle tissue under stress, especially in broilers [57]. This gene was enriched [58].…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, the potassium channel may be related to the amount of L-arginine in muscle [22][23][24]. Interestingly, if the content of adenosine triphosphate (ATP), a glucose metabolite in the muscle, changes as insulin manages skeletal muscle glucose uptake, the content of inosine, which is a repeatedly degraded form of ATP, may also be affected [25,26]. For the same reason, it could be concluded that the KCNIP4 gene on the significant region in GGA4 encodes a potassium channel interacting protein.…”
Section: Candidate Genes In the Shared Significant Region Of The Argi...mentioning
confidence: 99%
“…Furthermore, muscle contraction can stimulate Glut4 and 5′ AMP-activated protein kinase (AMPK) expression to increase adenosine triphosphate (ATP) production [ 10 , 11 ]. ATP hydrolysis, via the interaction between actin and myosin molecules, generates the force for muscle contraction [ 12 ].…”
Section: Introductionmentioning
confidence: 99%