Insights Sobre Neuromarketing E Neurociência

Pereira, Alexandre José Araújo; Fernandes, Ana Gabriela Lopes; Celestino, Égon José Mateus; Barros, Ivana Soares; Santos, Ivan Lucas Duarte dos; Silva, Izabela Souza da; Ribeiro, José Jailton; Fernandes, Maria Goretti; SANTOS, PALOMA DANIELE DE OLIVEIRA; Lima, Paulo Autran Leite; Oliveira, Silvia de Freitas Pedrosa de Pessoa; CARVALHO, THIAGO DE AZEVEDO FERRAZ DE NUNES

doi:10.29327/539816

Cited by 1 publication

(1 citation statement)

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“…In the case of Gram-positive bacteria, such as those included in this study, it could be expected that their thicker cell wall with a high content of peptidoglycan decreases the efficiency of Ag NPs (Rai et al, 2012), but our study has shown the contrary. Regarding the mechanism of antimicrobial action against filamentous fungi, available studies are limited, but it has been proven that exposure to Ag NPs causes prominent injury associated with membrane disruption of mycelia, as well as with ROS generation, Frontiers in Materials frontiersin.org downregulation of stress enzymes, and disruption of endogenic antioxidant machinery (Pereira et al, 2014;Kumari et al, 2019). ZnO NPs revealed antifungal (against A. niger, A. versicolor, Rhizopus nigricans, Saccharomycetes, and Mucor spp.)…”

Section: Sample Setmentioning

confidence: 99%

Alternative mitigating solutions based on inorganic nanoparticles for the preservation of cultural heritage

Corbu,

Dumbravă,

Marinescu

et al. 2023

Front. Mater.

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Introduction: Biodeterioration is a big challenge for the preservation of cultural heritage objects and for the community’s safety, fostering the search for novel methods effective in removing microbial biofilms and subsequent biodeterioration. In this context, nanoparticles (NPs) are considered an interesting alternative, based on their unique physico-chemical and biological properties.Methods: The present study aimed to evaluate the antimicrobial efficiency of Ag, Au, Cu, and ZnO NPs against a significant number of filamentous fungi and bacterial strains isolated from wooden and stone cultural heritage objects from different Romanian regions, as well as from museum collections, with the final goal to establish their potential to develop novel preservation strategies, which have high efficiency and low ecotoxicity.Results: Six types of nanoparticles (NPs) based on Ag, Au, Cu, and ZnO were synthesized and characterized for their physico-chemical properties, ecotoxicity, and efficacy against 75 filamentous fungi and 17 bacterial strains isolated from wooden and stone cultural heritage objects (15th–19th century). The results showed that all synthetized NPs are homogeneous, demonstrating a good stabilizing coating, and have spherical or triangular shapes, with sizes between 9 and 25 nm. The highest antifungal efficiency has been recorded for Ag NPs, followed by Cu NPs and ZnO NPs, with the most susceptible strains being Aspergillus montevidensis, Penicillium commune, Penicillium corylophilum, Bacillus megaterium, and B. cereus. The Cu NPs and ZnO NPs decreased the capacity of microbial strains to adhere to the inert substratum. The influence of the tested NPs against enzyme/organic acid production varied depending on the NP types and by species.Conclusion: The obtained results are promising for the development of efficient and economical alternative solutions for heritage preservation, showing high antimicrobial activity against the prevalent fungal and bacterial strains involved in the biodeterioration of Romanian heritage objects.

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Section: Sample Setmentioning

confidence: 99%