The aim of the investigation was to determine the most appropriate avenues for further implementation of the European concept of anti-corruption. To carry out this article, general and special research methods have been applied, such as systems analysis, dialectical, formal logical and structural functional methods, as well as a series of empirical methods. Statistical analysis has been used to demonstrate anti-corruption measures, undertaken in 2016 - 2020. The anti-corruption mechanism has been analyzed through the prism of combined institutional and instrumental systems, with the aim of preventing corruption. The priorities for transforming the anti-corruption mechanism have been defined as follows: (a) increased accountability for corruption offences; (b) introduction and appropriate application of corruption detection tools. It is concluded that the current trend demonstrates a decline in the implementation of anti-corruption preventive tools in Ukraine due to the following factors: change of the vector of public interest towards compliance with anti-Covid-19 measures, destabilization of authority and lack of collaboration between authorized subjects in solving corruption problems.