Insomnia and Cognitive Performance

Brownlow, Janeese A.; Miller, Katherine E.; Gehrman, Philip

doi:10.1016/j.jsmc.2019.10.002

Cited by 133 publications

(82 citation statements)

References 33 publications

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“…This study suggests that insomnia may be positively related to CCFs directly and indirectly via SA. Previous studies reported that insomnia is linked to cognitive performance [ 27 , 28 , 29 ], and generalized anxiety disorder moderated the associations between insomnia and cognitive function [ 30 ]. To our knowledge, the present study is the first to suggest that SA may mediate the relationship between insomnia and CCFs.…”

Section: Discussionmentioning

confidence: 99%

“…A recent study reported that insomnia complaints are linked to daytime cognitive performance in individuals with insomnia [ 27 ]. A meta-analysis revealed that individuals with insomnia exhibited small to moderate cognitive deficits for working memory, episodic memory and some aspects of executive functioning compared to healthy sleepers [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

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Mediating Roles of Cognitive Complaints on Relationships between Insomnia, State Anxiety, and Presenteeism in Japanese Adult Workers

Toyoshima

Inoue

Shimura

et al. 2021

IJERPH

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Complaints of cognitive functions (CCFs), defined as subjective cognitive dysfunction, affect social function; additionally, for workers, this condition is an important factor in presenteeism and mediates the effect of depressive symptoms on presenteeism. This study aimed to investigate whether CCFs mediate the relationships among insomnia, state anxiety (SA), and presenteeism. Participants were 471 Japanese adult workers evaluated using the Athens Insomnia Scale, State-Trait Anxiety Inventory (Form Y), Cognitive Complaints in Bipolar Disorder Rating Assessment, and Work Limitations Questionnaire 8 to assess insomnia, SA, CCFs, and presenteeism, respectively. Path analysis was used to evaluate the correlations between variables. CCFs significantly mediated the associations among insomnia, SA, and presenteeism. To address the presenteeism associated with insomnia and SA, it may be useful to assess the mediating roles of CCFs.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Mediating Roles of Cognitive Complaints on Relationships between Insomnia, State Anxiety, and Presenteeism in Japanese Adult Workers

Toyoshima

Inoue

Shimura

et al. 2021

IJERPH

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“…In this study, 4-week trazodone treatment improved the cognitive function of CSVD patients instead of impairing it. SWS and sleep continuity are both critical to cognitive function, such as memory consolidation, concentration, alertness, and working memory ( 41 , 42 ). Since trazodone increased the sleep continuity and the ratio of SWS in the present study, it is reasonable to speculate that the cognitive impairment in CSVD patients could be attenuated along with the relief of insomnia.…”

Section: Discussionmentioning

confidence: 99%

Effects of Trazodone on Sleep Quality and Cognitive Function in Arteriosclerotic Cerebral Small Vessel Disease Comorbid With Chronic Insomnia

et al. 2020

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Background Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was performed to explore the effects of trazodone on sleep quality and cognitive function in CSVD comorbid with chronic insomnia. Methods This was a randomized, double-blind, placebo-controlled pilot study. Forty patients suffering from arteriosclerotic CSVD and insomnia were recruited from an outpatient clinic. Participants were randomized individually to receive either trazodone (study group) or a placebo (control group) for 4 weeks. The primary outcome was the cognitive score on the Montreal Cognitive Assessment scale (MoCA). Secondary outcomes included sleep parameters measured with polysomnography (PSG) and the Pittsburgh Sleep Quality Index. Results Trazodone caused significantly better improvements in concentration and recall abilities, measured with MoCA, as well as in PSG parameters such as sleep efficiency, N3 sleep ratio, and sleep continuity than the placebo, with no significant differences in the occurrence of side effects. The improvement of sleep quality was correlated with increased concentration and recall abilities. Conclusions A low dose of trazodone seems acceptable and effective in reducing insomnia severity and improving concentration and recall abilities in this pilot study. The improvement of cognition could be achieved by alleviation of insomnia severity. Considering the high incidence of insomnia in CSVD patients, the results of this preliminary study support the use of low-dose trazodone to deal with insomnia and cognitive impairment in CSVD.

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“…Furthermore, this finding is consistent with previous studies reporting an association between decreased sleep continuity and cognitive decline. 21,[53][54][55][56][57] The association between sleep and trauma-related symptoms has been widely studied, 58,59 and REM sleep and SWS have been found to play a role in altered cognitive performance in traumatized people. [59][60][61] Furthermore, a relationship has been established between reduced arousal during sleep and adaptive cognitive processing of traumatic experiences.…”

Section: Discussionmentioning

confidence: 99%

Polysomnographic Sleep and Attentional Deficits in Traumatized North Korean Refugees

Lee¹,

Jeon²,

Kim³

et al. 2021

NSS

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Introduction: Attentional deficits and sleep problems are common in refugees who have experienced trauma. In the present study, we used polysomnography (PSG) to investigate the relationship between attentional deficits and objective measures of sleep structure in traumatized North Korean refugees. Methods: We recruited 32 North Korean refugees (mean age = 33.78 ± 14.33 years) and 39 South Korean participants (mean age = 35.03 ± 11.08 years). Sustained attention and divided attention were assessed using the Computerized Attention Test. We conducted an overnight PSG to objectively assess sleep structure. The participants also completed the

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Insomnia and Cognitive Performance

Cited by 133 publications

References 33 publications

Mediating Roles of Cognitive Complaints on Relationships between Insomnia, State Anxiety, and Presenteeism in Japanese Adult Workers

Mediating Roles of Cognitive Complaints on Relationships between Insomnia, State Anxiety, and Presenteeism in Japanese Adult Workers

Effects of Trazodone on Sleep Quality and Cognitive Function in Arteriosclerotic Cerebral Small Vessel Disease Comorbid With Chronic Insomnia

Polysomnographic Sleep and Attentional Deficits in Traumatized North Korean Refugees

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