Insomnia, hypnotic use, and health-related quality of life in a nationally representative sample

Scalo, Julieta; Desai, Pooja; Rascati, Karen L.

doi:10.1007/s11136-014-0842-1

Cited by 31 publications

(24 citation statements)

References 58 publications

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“…General recommendations for MIDs range from 2 to 4 points to be considered clinically important [41]. A difference of five points in SF-12 summary scores, a common MID threshold, has also been suggested as a meaningful [26,42]. Therefore, interpretations are difficult when an observed difference is smaller but statistically significant [43].…”

Section: Discussionmentioning

confidence: 99%

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Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

Darchia

Oniani

Sakhelashvili

et al. 2018

IJERPH

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The extent to which sleep disorders are associated with impairment of health-related quality of life (HRQoL) is poorly described in the developing world. We investigated the prevalence and severity of various sleep disorders and their associations with HRQoL in an urban Georgian population. 395 volunteers (20–60 years) completed Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, STOP-Bang questionnaire, Insomnia Severity Index, Beck Depression Inventory-Short Form, and Short Form Health Survey (SF-12). Socio-demographic data and body mass index (BMI) were obtained. The prevalence of sleep disorders and their association with HRQoL was considerable. All SF-12 components and physical and mental component summaries (PCS, MCS) were significantly lower in poor sleepers, subjects with daytime sleepiness, apnea risk, or insomnia. Insomnia and apnea severity were also associated with lower scores on most SF-12 dimensions. The effect of insomnia severity was more pronounced on MCS, while apnea severity—on PCS. Hierarchical analyses showed that after controlling for potential confounding factors (demographics, depression, BMI), sleep quality significantly increased model’s predictive power with an R2 change (ΔR2) by 3.5% for PCS (adjusted R2 = 0.27) and by 2.9% for MCS (adjusted R2 = 0.48); for the other SF-12 components ΔR2 ranged between 1.4% and 4.6%. ESS, STOP-Bang, ISI scores, all exerted clear effects on PCS and MCS in an individual regression models. Our results confirm and extend the findings of studies from Western societies and strongly support the importance of sleep for HRQoL. Elaboration of intervention programs designed to strengthen sleep-related health care and thereof HRQoL is especially important in the developing world.

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Section: Discussionmentioning

confidence: 99%

“…Although neither the SF-36 nor the SF-12 includes items specific to sleep [3,26], both instruments have been extensively used to assess the association between HRQoL and sleep disorders.…”

Section: Methodsmentioning

confidence: 99%

Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

Darchia

Oniani

Sakhelashvili

et al. 2018

IJERPH

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“…Although insomnia is linked to worsened HRQOL in adults9 and difficulty falling asleep and nocturnal awakenings have been shown to impair HRQOL in preschool age children22, the impact of insomnia on HRQOL in school age children has not been previously reported. We performed a secondary analysis of the Tucson Children’s Assessment of Sleep Apnea (TuCASA) study to determine the effects of intermittent and persistent insomnia on HRQOL in children.…”

mentioning

confidence: 99%

Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort

Combs

Goodwin

Quan

et al. 2016

Sci Rep

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Insomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 ± 1.6 years, age at data analysis 15.0 ± 1.8 years) over 7 years. International Classification of Sleep Disorders, second edition (ICSD2) derived insomnia was seen intermittently in 27% of children, and was persistent in 4%. Children reporting ICSD2-derived insomnia had lower HRQOL. Additionally, the presence of insomnia was associated with an increased risk of reporting a new medical condition (intermittent insomnia odds ratio 5.9 [95% CI 1.3–26.7, p = 0.04], persistent insomnia odds ratio 8 [95% CI 2.3–27.7, p = 0.001]). Persistent ICSD2-derived insomnia was associated with an increased risk of reporting a new medication (odds ratio 4.9 (95% CI 1.0–23.6), p = 0.049), and reporting a new psychiatric medication (odds ratio 13.7, 95% CI: 2.6–73.5, p = 0.002). These associations were present even after adjusting for socioeconomic factors and the presence of obstructive sleep apnea. Insomnia in children is associated with worsened HRQOL and health outcomes.

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“…It could be that as people become older or receive longer CAPD therapy, the symptoms of sleep disorders and depression become worse [23], affecting their satisfaction with life [24]. …”

Section: Discussionmentioning

confidence: 99%

Effect of Sedative-Hypnotic Medicines on Mortality in Peritoneal Dialysis Patients with Sleep Disorders: A Retrospective Cohort Study

Zhou

Yin

et al. 2017

Blood Purif

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Background: Sedative-hypnotic medication is widely used among continuous ambulatory peritoneal dialysis (CAPD) patients with sleep disorders; however, its effect on mortality has rarely been investigated. Methods: Logistic regression was employed to identify factors associated with sedative-hypnotic medication, whose effect on mortality was evaluated by Cox proportional hazards models. Results: A total of 146 CAPD patients with sleep disorders were recruited, of which 46 patients (31.5%) used either benzodiazepines or zolpidem. Sedative-hypnotic medication was more frequently used by older patients and those with longer duration of CAPD therapy and there was no significant association between sedative-hypnotic medicines and all-cause mortality after adjusting for age, gender, diabetes, cardiovascular disease, and duration of CAPD. Conclusion: Sedative-hypnotic medication was more often used by older patients and patients with a longer duration of CAPD. There was no association between these agents and all-cause mortality in CAPD patients with sleep disorders.

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Insomnia, hypnotic use, and health-related quality of life in a nationally representative sample

Cited by 31 publications

References 58 publications

Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

Relationship between Sleep Disorders and Health Related Quality of Life—Results from the Georgia SOMNUS Study

Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort

Effect of Sedative-Hypnotic Medicines on Mortality in Peritoneal Dialysis Patients with Sleep Disorders: A Retrospective Cohort Study

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