This study investigates challenges faced by investigative journalists in Latin America, one of the most dangerous places in the world for reporters. Guided by the hierarchy of influences model, we analyzed answers from 1,543 journalists, journalism educators, and journalism students in the region. We identified both single and multilevel constraints impeding investigative reporting in Latin America. Single-level influences are those that are better analyzed by focusing on one level of the hierarchical model. These included individual (lack of training), routine (relationships with sources), organizational (media ownership), and institutional influences (censorship). However, results also suggest there are certain types of influences that are better suited for analysis combining all levels. Despite two decades of media liberalization, crime and corruption, state violence against the press, and the lack of a free-speech culture cut across all layers, posing severe constraints to investigative reporting in Latin America.