Instant Mercury Ion Detection in Industrial Waste Water with a Microchip Using Extended Gate Field-Effect Transistors and a Portable Device

Sukesan, Revathi; Chen, Yi-Ting; Shahim, Suman; Wang, Shin-Li; Sarangadharan, Indu; Wang, Yulin

doi:10.3390/s19092209

Cited by 13 publications

(15 citation statements)

References 41 publications

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“…Moreover, the sensor had good specificity towards Hg 2+ even in complex matrices. Later, they constructed Hg-ISHEMT sensors with a user interface that could estimate the concentration of Hg 2+ in an unknown solution [ 206 ]. Interestingly, the response time of this sensor was observed to be further improved up to 5 min, compared to previous Hg-ISHEMT sensor response time (~10 min).…”

Section: Iii-v Materials High Electron Mobility Transistor (Hemt)mentioning

confidence: 99%

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

et al. 2021

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Heavy metal pollution remains a major concern for the public today, in line with the growing population and global industrialization. Heavy metal ion (HMI) is a threat to human and environmental safety, even at low concentrations, thus rapid and continuous HMI monitoring is essential. Among the sensors available for HMI detection, the field-effect transistor (FET) sensor demonstrates promising potential for fast and real-time detection. The aim of this review is to provide a condensed overview of the contribution of certain semiconductor substrates in the development of chemical and biosensor FETs for HMI detection in the past decade. A brief introduction of the FET sensor along with its construction and configuration is presented in the first part of this review. Subsequently, the FET sensor deployment issue and FET intrinsic limitation screening effect are also discussed, and the solutions to overcome these shortcomings are summarized. Later, we summarize the strategies for HMIs’ electrical detection, mechanisms, and sensing performance on nanomaterial semiconductor FET transducers, including silicon, carbon nanotubes, graphene, AlGaN/GaN, transition metal dichalcogenides (TMD), black phosphorus, organic and inorganic semiconductor. Finally, concerns and suggestions regarding detection in the real samples using FET sensors are highlighted in the conclusion.

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Section: Iii-v Materials High Electron Mobility Transistor (Hemt)mentioning

confidence: 99%

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

et al. 2021

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“…There are limited articles available on the detection of Pb [ 31 ] and Hg [ 91 ] in drinking water using DGISFETs. Recently An et al [ 92 ] reported detection of Hg using graphene aptasensor on flexible PEN substrates with a detection limit of 10 pM.…”

Section: Applications Of Dgisfetsmentioning

confidence: 99%

Dual‐gate ion‐sensitive field‐effect transistors: A review

Bhatt

Panda

2021

Electrochemical Science Adv

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Ion-sensitive field-effect transistors (ISFETs) are electrochemical sensors that work on the principle of metal-oxide field-effect transistors. Dual-gate ionsensitive field-effect transistors (DGISFETs) are an advanced version of ISFETs with an additional gate dielectric, resulting in sensitivity enhancement on account of the coupling of the capacitances of the two gate dielectrics. ISFETs were demonstrated first in 1970 and there are several review articles available on various aspects of ISFETs; although DGISFETs were first demonstrated in 2010, there are no focused review articles on this subject and this is the motivation of present work. This review has explored the understanding of the basic platform, the working principle, different structures, and various applications of DGISFETs. Further, types of DGISFETs are elaborated based on their architecture, material used for fabrication, and substrates used for such devices with utilization of different semiconductor and gate dielectric materials, rigid and flexible substrates. The state-of-the-art of rigid and flexible DGISFETs is discussed for various applications. Challenges in the fabrication and utilization of DGISFETs in various fields and further advances are discussed.

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“…With the widespread use of pesticides and fertilizers, some toxic small molecules and heavy metal ions such as bis(2-ethylhexyl) phthalate (DEHP), nitrite, and Hg 2+ are unavoidable. Several studies have demonstrated those molecules and ions are serious threats to human health and the environment [48,49,50]. Sensitive detections for these toxic substances have been achieved by using gas chromatography-mass spectrometry (GC/MS), inductively coupled plasma mass spectrometer, and high performance liquid chromatography (HPLC) with UV and diode array detectors [51,52,53,54,55].…”

Section: Aptamer-based Sers Probes In Quantitative Analysis and Bimentioning

confidence: 99%

Development and Application of Aptamer-Based Surface-Enhanced Raman Spectroscopy Sensors in Quantitative Analysis and Biotherapy

Wang

Zhao

et al. 2019

Sensors

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Surface-enhanced Raman scattering (SERS) is one of the most special and important Raman techniques. An apparent Raman signal can be observed when the target molecules are absorbed onto the surface of the SERS substrates, especially on the “hot spots” of the substrates. Early research focused on exploring the highly active SERS substrates and their detection applications in label-free SERS technology. However, it is a great challenge to use these label-free SERS sensors for detecting hydrophobic or non-polar molecules, especially in complex systems or at low concentrations. Therefore, antibodies, aptamers, and antimicrobial peptides have been used to effectively improve the target selectivity and meet the analysis requirements. Among these selective elements, aptamers are easy to use for synthesis and modifications, and their stability, affinity and specificity are extremely good; they have been successfully used in a variety of testing areas. The combination of SERS detection technology and aptamer recognition ability not only improved the selection accuracy of target molecules, but also improved the sensitivity of the analysis. Variations of aptamer-based SERS sensors have been developed and have achieved satisfactory results in the analysis of small molecules, pathogenic microorganism, mycotoxins, tumor marker and other functional molecules, as well as in successful photothermal therapy of tumors. Herein, we present the latest advances of the aptamer-based SERS sensors, as well as the assembling sensing platforms and the strategies for signal amplification. Furthermore, the existing problems and potential trends of the aptamer-based SERS sensors are discussed.

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Instant Mercury Ion Detection in Industrial Waste Water with a Microchip Using Extended Gate Field-Effect Transistors and a Portable Device

Cited by 13 publications

References 41 publications

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

Ten Years Progress of Electrical Detection of Heavy Metal Ions (HMIs) Using Various Field-Effect Transistor (FET) Nanosensors: A Review

Dual‐gate ion‐sensitive field‐effect transistors: A review

Development and Application of Aptamer-Based Surface-Enhanced Raman Spectroscopy Sensors in Quantitative Analysis and Biotherapy

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