Institutional Outbreak of Varicella in a Child Welfare Institute in Chandigarh, North India

Singh, Mini P.; Rungta, Tripti; Kumar, Archit; Goyal, Kapil; Bharti, Bhavneet; Ratho, Radha Kanta

doi:10.4103/ijmm.ijmm_18_264

Cited by 1 publication

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“…After primary infection, VZV sets latency in dorsal root ganglion cells, as is typical with alphaherpesviruses. [2] The presence of the Varicella-Zoster is linked into two distinct illnesses. First is varicella, a common and highly contagious illness in young people.…”

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confidence: 99%

Prevalence in Varicella Zoster Virus DNA in Inflammatory Bowel Disease Patients

Venkatachalam,

2024

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Individuals with an Inflammatory-bowel-disease are at a higher risk of contracting the virus. The prevalence of VZV in IBD patient’s is a particularly concerning, as it has been-reported to be highly contagious, severe, and in some cases fatal in patients with colitis. This study was aim to be evaluate the prevalence of VZV in individuals with IBD. Methods: Serum and biopsy-sample of large-intestine specimens from patients with IBD (Ulcerative-Colitis-(n = 31), patients with Crohn’s-disease-(n = 23)) and control group of non-IBD-(n = 21) were analysed the anti-VZV-IgG presence from done by ELISA and Viral-DNA of VZV by Nested-PCR. All biopsy-samples were viral VZV-DNA was analysed done by using Nested-PCR assay. In this study, a statistical-model was used to compare prevalence of the virus in IBD-patient and non-IBD patients. Results: all IBD-case patients, 47 and 09 were positive for serum of anti-VZV Antibodies by ELISA and tissue-Biopsy of VZV-DNA by nested PCR, and to non-IBD control group,19 and 00 were positive for serum of anti-VZV Antibodies by ELISA and Tissue-Biopsy of VZV-DNA by Nested-PCR-Method. Analyses of nested-PCR of results showed in a robust correlation in between VZV prevalence and Inflammatory-bowel-disease. Conclusion: The detection of VZV in routine samples might be an indicator for the inclusion of the vaccine for VZV in the childhood immunization-program has been proposed, Whereas the VZV-vaccine is widely available, and as the vaccine has been quite effective in preventing the complications associated with VZV infection.

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Section: ) Introductionmentioning

confidence: 99%

Prevalence in Varicella Zoster Virus DNA in Inflammatory Bowel Disease Patients

Venkatachalam,

2024

Preprint

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Institutional Outbreak of Varicella in a Child Welfare Institute in Chandigarh, North India

Cited by 1 publication

References 40 publications

Prevalence in Varicella Zoster Virus DNA in Inflammatory Bowel Disease Patients

Prevalence in Varicella Zoster Virus DNA in Inflammatory Bowel Disease Patients

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