Insufficiency of Cellular Energy (ICE) May Precede Neurodegeneration in Alzheimer’s Disease and Be Treatable via the Alternative Cellular Energy (ACE) Pathway

Martin, William J.

doi:10.4236/aad.2017.61001

Cited by 8 publications

(13 citation statements)

References 62 publications

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“…4) Neurological and psychiatric illnesses in which sets of neuronal cells are apparently either hyperactive or quiescent due to an insufficiency of cellular energy (ICE) from the ACE pathway [54]. An important focus is on the potential therapy of Alzheimer's disease [55].…”

Section: Discussionmentioning

confidence: 99%

Tissue Regeneration without Scarring Achieved by Enhancing the Alternative Cellular Energy (ACE) Pathway

Martin¹

2017

JCDSA

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The inflammatory and fibrous responses to injuries are painful and are inhibitory to the regeneration of specialized cells. The fibrous scarring of skin injuries can also be disfiguring. Cells obtain energy not only from the metabolism of food, but also via the alternative cellular energy (ACE) pathway. The ACE pathway is reflected in a dynamic (kinetic) quality of the body's fluids. It is postulated to result from the absorption of an environmental force called KELEA (kinetic energy limiting electrostatic attraction). The body's ACE pathway can be enhanced by the parental administration and even the oral consumption of products comprising KELEA activated water. One of these products, termed Enercel, was originally considered a complex homeopathic remedy. Another product is water containing electrolysis-generated, coppersilver-citrate (CSC) complexes. This product was initially formulated to be bacteriocidal, especially for Gram positive bacteria. This article describes the independent successful use of each of these two products in achieving essentially painless, scar-free healing of skin injuries. The skin injuries were due to a variety of causes including: vascular insufficiency from diabetes; hot water burn; penetrating object; chronic infection; and surgical incision. It is proposed that the ACE pathway increases the resilience of cells of the innate immune system to the triggering of an inflammatory reaction by "danger signals" released from damaged tissues. KELEA activated water should be widely available for the urgent therapy of burns and other traumatic injuries to the skin. ACE pathway enhancing modalities also need to be evaluated in the repair of cellular damage occurring to the heart, brain and other internal organs of the body.

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Section: Discussionmentioning

confidence: 99%

Tissue Regeneration without Scarring Achieved by Enhancing the Alternative Cellular Energy (ACE) Pathway

Martin¹

2017

JCDSA

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“…For instance, it is proposed that KELEA can function in maintaining more stable cellular electrical membrane potential [1,2]. This appears to be particularly relevant to the functioning of neuronal and neurosensory cells.…”

Section: Alternative Cellular Energy (Ace) Pathwaymentioning

confidence: 99%

“…An extrapolation of this hypothesis is that neuronal and neurosensory cells may initially respond to ICE by becoming hyper-excitable. As discussed elsewhere [1,2], this is likely to be a non-sustainable adaptation, in which case the affected neuronal and neurosensory cells would enter a phase in which although still viable, the cells would lack the energy required to perform their intended more specialized functions. Many neurological and psychiatric illnesses are consistent with symptoms arising from either hyper-excitable or functionally quiescent neuronal cells.…”

Section: The Ace Pathway and The Nervous Systemmentioning

confidence: 99%

“…A basic level of neuronal cell activity may be necessary to maintain effective KELEA attracting ability. Indeed, it is possible that if a sufficient level of activity can be achieved therapeutically, the energy attracting capacity of the brain may become self-sustaining [1,2]. Thus, unlike many pharmaceuticals that are intended for lifelong use, single or limited use of several CAM procedures can potentially achieve long-term remission of illness.…”

Section: Possible Attraction Of Kelea By Brain and Musclesmentioning

confidence: 99%

“…Yet, the work output of a typical human in terms of the functioning of different organ systems, muscular activities and maintaining body temperature are not explainable by the input of dietary calories [1,2]. To put this issue into perspective, the maximum available energy upon consumption of a diet of 2,000 Calories is less than that in a tenth of a gallon of gasoline (8.4 million versus 13 million joules).…”

Section: Introductionmentioning

confidence: 99%

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The Many Biological Functions of the Alternative Cellular Energy (ACE) Pathway

Martin¹

2017

IJCAM

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This article summarizes the known biological functions of the alternative cellular energy (ACE) pathway. It has been proposed that this pathway is powered by a natural force called KELEA (kinetic energy limiting electrostatic attraction). KELEA can be transferred to liquids, including water and body fluids. The absorption of KELEA results in a loosening and possible lengthening of the intermolecular bonding between the liquid molecules, along with an increase in the kinetic activity of the molecules. KELEA can also provide an energy source for biosynthetic chemical reactions, including the synthesis of lipids. Since many human illnesses are attributed to insufficienct cellular energy (ICE), procedures aimed at enhancing the ACE pathway are likely to be therapeutically useful. Some of these procedures are currently available for widespread clinical use once they receive regulatory approval. A consortium of interacting clinicians is envisioned to assist in optimizing the current procedures for enhancing the ACE pathway and to develop new approaches. Patient support groups can also assist in the evaluation of various self-directed therapeutic procedures. Collectively, these efforts should significantly decrease the existing costs of medical care and provide effective therapies for several major illnesses for which none presently exists. Keywords: IntroductionIt has been assumed that the cellular energy utilized by animals and humans is solely obtained from the Calories available in consumed food. Yet, the work output of a typical human in terms of the functioning of different organ systems, muscular activities and maintaining body temperature are not explainable by the input of dietary calories [1,2]. To put this issue into perspective, the maximum available energy upon consumption of a diet of 2,000 Calories is less than that in a tenth of a gallon of gasoline (8.4 million versus 13 million joules). A Calorie (kilocalorie) is 4,200 joules and is defined as the heat necessary to raise the temperature of a kilogram (Kg) of water by 1 o Centigrade (C). Over a 24-hour period, an individual weighing 75 kilograms and assumed to be composed essentially of water, requires 6.3 million joules (1,500 Calories) to maintain a body temperature of 37 °C if living in an environment with an average temperature of 17 °C (59 o Fahrenheit).[75 x (37-17) = 1,500]. Estimates of the work output of various organs within the body, such as the heart and brain, are generally based on oxygen consumption, which again incorrectly assumes that food metabolism is the sole source of cellular energy. Higher estimates of work output are obtained using measures of biosynthesis, fluid movements, muscular performance, electrical activity, etc. It is reasonable, therefore, to consider that there is a mechanism, other than consuming food, by which the body can acquire cellular energy. Beliefs in Non-Conventional EnergiesTraditional Oriental Medicine providers and Complementary Medicine (CAM) practitioners have long maintained that the body expr...

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2018

IJCAM

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Insufficiency of Cellular Energy (ICE) May Precede Neurodegeneration in Alzheimer’s Disease and Be Treatable via the Alternative Cellular Energy (ACE) Pathway

Cited by 8 publications

References 62 publications

Tissue Regeneration without Scarring Achieved by Enhancing the Alternative Cellular Energy (ACE) Pathway

Tissue Regeneration without Scarring Achieved by Enhancing the Alternative Cellular Energy (ACE) Pathway

The Many Biological Functions of the Alternative Cellular Energy (ACE) Pathway

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