Insufficient iodine nutrition may affect the thyroid cancer incidence in China

Abstract

Epidemiologic studies have focused on the effects of iodine intake on the risk of thyroid cancer. However, their relationship is still obscure. The objective of this study was to examine the association in the Chinese population. A new ecological study which combined the Annual Report of Cancer, the Survey of Iodine Deficiency Disorder Surveillance and the water iodine survey were conducted to analyze the relationship between iodine intake and the thyroid cancer incidence in China. In total, 281 counties were included. Thyroid cancer incidence was negatively correlated with the consumption rate of qualified iodized salt (CRQIS) and positively correlated with goiter prevalence (GP) of children aged 8˜10 years, residents’ annual income and coastal status. Areas with a low CRQIS and areas with a high GP had a relatively high incidence of thyroid cancer. Regression models showed that a low CRQIS and a high GP in children aged 8˜10 years (both reflecting iodine deficiency status) play a substantial role in thyroid cancer incidence in both males and females. Additionally, living in coastal areas and having a high annual income may also increase the risk of thyroid cancer. These findings suggest that mild iodine deficiency may contribute to the exceptionally high incidence of thyroid cancer in some areas in China. Maintaining appropriate iodine nutrition not only helps to eliminate IDD, but also may help to reduce the occurrence of thyroid cancer.

Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials

“…In 2019, out of 233,846 new cases and 45,575 deaths globally, China accounted for 16.71% and 15.88%, respectively [ 15 ]. The elevated prevalence of thyroid cancer in specific regions within China is potentially attributable to mild iodine deficiency [ 16 ]. Notably, regions such as Guangdong, Zhejiang, and Jiangsu have witnessed high incidence rates particularly among women, with variances of up to 45-fold between the least and most affected areas.…”

Analysis of the Rehabilitation Efficacy and Nutritional Status of Patients After Endoscopic Radical Thyroidectomy by Fast Track Surgery Based on Nutritional Support

“…However, radical thyroidectomy is difficult and prone to many postoperative complications. In addition, due to the pathological consumption of thyroid cancer, dysphagia symptoms, surgery and inflammation, a large amount of proteins and fats are consumed in the body, and patients may suffer from malnutrition status ( 15 , 16 ). One study ( 17 ) showed that patients with nutritional risk have a significantly higher incidence of postoperative infectious complications and a significantly longer hospital stay, so clinical workers need to pay attention to nutritional screening of surgical patients and the prognostic impact of nutritional risk on surgery.…”

Application of dual‐source computed tomography in the diagnosis of thyroid cancer and evaluation of biological behaviors

“…To our knowledge, the thyroid gland is a potent collector of iodine, 34 and both insufficient and excessive iodine intake can result in thyroid diseases and even exert an impact on TC, indicating that sustaining proper iodine nutrition may help lower the incidence of TC. 35 Interestingly, because of different attenuation coefficients of the same substance at different energy X-rays, dual-energy CT scanning technique not only easily distinguishes iodine from other different substances but also accurately and quantitatively calculates the IC in the region of interest. 17 Through DSCT scanning, our results unveiled lower levels of IC in plain CT and venous phase NIC in TC patients than those in patients with benign lesions.…”