Insulin and lipoprotein metabolism with special reference to the diabetic state

Acute pancreatitis due to diabetes: The role of hyperglycaemia and insulin resistance

“…Patients with DM have a higher incidence of obesity [65] and hypertriglyceridaemia [66,67]. Oral hypoglycaemic agents form an important part of therapy in DM [68].…”

Role of insulin in hepatic fatty acid partitioning: emerging concepts

“…It would therefore be expected that the composition of the diet is likely to be important in determining whether the liver is able to respond by decreasing its rate of TAG secretion during the prandial period, especially in insulin-deficient or -resistant states. The physiological requirement for the curtailment of hepatic TAG secretion during the prandial\early-absorptive phase is possibly more acute in individuals suffering from these conditions, owing to the exacerbation of hypertriglyceridaemia due to a diminished rate of clearance of chylomicron-TAG by peripheral tissues [183,184]. It would therefore be of interest to study the dependence of the extent of apoB "!!…”

Low serum apolipoprotein A1/B ratio is associated with proliferative diabetic retinopathy in type 2 diabetes

“…Free fatty acids are elevated in individuals with type 2 diabetes [10]. Unlike type 2 diabetic patients, type 1 diabetic patients usually exhibit a normal conventional lipid profile [11,12]. That is the reason why conclusive results are still lacking, though there are several studies on the relationship between serum lipid profile and DR in type 1 diabetes [4,5].…”