Insulin resistance in patients with end-stage renal disease on hemodialysis: effect of short-term erythropoietin therapy

Kasem, Heba E.; Shehab-Eldin, W; Shebl, Islam S; Sonbol, Ahmed; Kamel, Mai A.

doi:10.4103/jesnt.jesnt_25_19

Cited by 1 publication

(1 citation statement)

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“…Studies suggest variable pancreatic beta cell function in response to IR in ESRD, resulting in glucose intolerance in some patients. However, management of IR in patients on hemodialysis is multifaceted (Kasem et al, 2020). Treatment of IR in patients with CKD can be achieved by hemodialysis, angiotensin-converting enzyme inhibitors, thiazolidinedione, and treatment of calcium and phosphate (Kasem et al, 2020).…”

Section: -Homeostasis Model Assessment Insulin Sensitivity (Homa2%ir)...mentioning

confidence: 99%

Insulin Resistance in End-Stage Renal Disease Patients: A Review

Twaij

Al‐Hakeim

2023

Egyptian Academic Journal of Biological Sciences. C, Physiology

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Many studies have found effects on the body and active products insulin state at near and long-term parameters in end-stage renal disease (ESRD) patients. Consequently, studying chemical molecules that cause tissue damage to kidneys is essential for understanding the mechanism of effect and available treatment prospects. Which includes some factors of insulin, Homeostasis Model Assessment insulin sensitivity (HOMA2%IR), Homeostasis Model Assessment sensitivity for cell (HOMA2%S), Homeostasis Model Assessment state beta cell function (HOMA2%B) parameters. The published papers on changes in the effects of IR products of patients were reviewed, and the explanations obtained from previous research were collected. It is concluded from this review that causes an increase in parameters in patients with ESRD leads to neurodegeneration and disorders affect the beta cell to produce insulin, which leads to severe damage to patients health that requires therapeutic intervention to reduce the harmful effects of parameters on the health of patients.

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Section: -Homeostasis Model Assessment Insulin Sensitivity (Homa2%ir)...mentioning

confidence: 99%