2017
DOI: 10.20944/preprints201705.0189.v1
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Insulin Secretion with the Effect of Loureirin B through K<sub>ATP </sub>Channel&ndash;Dependent Pathway

Abstract: The development of new diabetes drugs continues to be explored. Loureirin B, a flavonoid, extracted from Dracaena cochinchinensis, has been confirmed to increase insulin secretion and decrease blood glucose levels. For understanding the mechanism, a series of experiments had been employed based on computational methods and cell experiments. The insulin secretion significantly increased with the incubation of 0.01μM loureirin B for 4 hours. The viability of Ins-1 cells showed no significant difference with the … Show more

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