As recently reported in the New York Times (Stack, 2019), sexually transmitted infections (STIs), including chlamydia, gonorrhea, and syphilis diagnoses, continue to rise in the U.S. despite current public health efforts. Rates of chlamydia have reached an all-time high with 1.8 million cases in 2018 (Centers for Disease Control and Prevention, 2019c) (Fig. 1). Gonorrhea and syphilis infections have also increased 39% and 42%, respectively, from 2014 to 2018 (Figs. 2, 3). Women, adolescents and young adults, and gay, bisexual, and other men who have sex with men (MSM) continue to bear a disproportionate burden of STIs. Sixtyfive percent of chlamydia cases were reported in women, and of all reported cases of chlamydia among women, 68% were among young women 15-24 years of age. Rates of chlamydia are lower in men compared to women, likely due to screening recommendations for women, but diagnoses increased 38% from 2014 to 2018 in men. Rates of gonorrhea have increased 79% among men and 45% among women from 2014 to 2018. The increased rates among men may reflect screening recommendations for MSM (Table 1). Gonorrhea rates continue to be the highest among young adults 20-24 years of age (702.6 and 720.0 out per 100,000 cases of women and men, respectively). Men accounted for