Intakes, Adequacy, and Biomarker Status of Iron, Folate, and Vitamin B12 in Māori and Non-Māori Octogenarians: Life and Living in Advanced Age: A Cohort Study in New Zealand (LiLACS NZ)

Abstract

Advanced-age adults may be at risk of iron, folate, and vitamin B12 deficiency due to low food intake and poor absorption. This study aimed to investigate the intake and adequacy of iron, folate, and vitamin B12 and their relationship with respective biomarker status. Face-to-face interviews with 216 Māori and 362 non-Māori included a detailed dietary assessment using 2 × 24-h multiple pass recalls. Serum ferritin, serum iron, total iron binding capacity, transferrin saturation, red blood cell folate, serum folate, serum vitamin B12 and hemoglobin were available at baseline. Regression techniques were used to estimate the association between dietary intake and biomarkers. The Estimated Average Requirement (EAR) was met by most participants (>88%) for dietary iron and vitamin B12 (>74%) but less than half (>42%) for folate. Increased dietary folate intake was associated with increased red blood cell (RBC) folate for Māori (p = 0.001), non-Māori (p = 0.014) and serum folate for Māori (p < 0.001). Folate intake >215 µg/day was associated with reduced risk of deficiency in RBC folate for Māori (p = 0.001). Strategies are needed to optimize the intake and bioavailability of foods rich in folate. There were no significant associations between dietary iron and vitamin B12 intake and their respective biomarkers, serum iron and serum vitamin B12.

Ageing badly: indicators of old-age structure in Australia and New Zealand

“…Premature adult mortality before the age of 60 years has improved for all populations, but mortality ratios show little change since 2000, with Aboriginal at nearly four-fold that of all Australians, and Māori nearly three-fold that of non-Māori. 16 These findings may be attributed to nutritional inadequacy among older Māori 17 and smoking rates that are more than twice the smoking rate in the general population; 18 rates of dementia rapidly becoming a health priority in Australian Aboriginal communities; 19 and high rates of diabetes and renal failure accounting for 28% of all Australian Aboriginal deaths. 20 Frailty is prevalent and emerging at a younger age than expected in remote-living Aboriginal Australians, with rates substantially higher than in other populations.…”

Research antianemic action of the iron (IV) clathrochelate complexes on the sickling piglets

“…У сучасній ветеринарній медицині для лікування тварин за ферумодефіцитної анемії та її профілактики застосовують препарати Феруму (ІІ) або Феруму (ІІІ): пероральне введення солей Феруму (Maes et al, 2011;Svoboda et al, 2015) та парентеральне введення ферумодекстранових препаратів (Meier et al, 2011;Peña-Rosas et al, 2015;Pillay et al, 2018). Їхнім недоліком є низький відсоток всмоктування, що не забезпечує необхідного фармакологічного ефекту (Ma et al, 2017).…”

Antianemic action of the iron (IV) clathrochelate complexes

“…In modern veterinary medicine for the prevention and treatment of iron deficiency anemia of animals, iron (II) and iron (III) drugs are used: oral administration of iron salts (Maes et al, 2011;Svoboda et al, 2015) and parenteral administration of iron dextran drugs (Meier et al, 2011;Peña-Rosas et al, 2015;Pillay et al, 2018). Their disadvantage is a low percentage of suction that does not provide the necessary pharmacological effect.…”