We construct a two-parameter deformed SUSY algebra for the system of n ordinary fermions and n(q 1 , q 2 )-deformed bosons called Fibonacci oscillators with SU q 1 /q 2 (n)-symmetry. We then analyze the Fock space representation of the algebra constructed. We obtain the total deformed Hamiltonian and the energy levels together with their degeneracies for the system. We also consider some physical applications of the Fibonacci oscillators with SU q 1 /q 2 (n)-symmetry, and discuss the main reasons to consider two distinct deformation parameters.