Integral dose: Comparison between four techniques for prostate radiotherapy

Abstract

The highest total dose absorbed in normal tissue was observed with the use of a robotic radiosurgery system and TomoTherapy. These results demonstrate that the exposure of healthy tissue is a dosimetric factor which differentiates the dose delivery methods.

Stereotactic radiosurgery of prostate cancer – dose distribution for VMAT and CyberKnife techniques

“…We raised a question whether dose distributions that are calculated for two different groups of patients treated with VMAT technique and CyberKnife are comparable. The results are consistent with the literature [23,24], which relate to the comparison of dose distributions in various techniques. The applied coefficients of treatment plan evaluation, Quality of Coverage, Conformity Index, Conformal Index and Radiation Planning Index, also indicate that both treatment techniques are acceptable.…”

Image-guided hypofractionated proton beam therapy for low-risk prostate cancer: Analysis of quality of life and toxicity, PCG GU 002

“…Therefore, in the present protocol, we proposed to combine a hypofractionated approach that benefits from the low ˛/ˇ ratio of prostate cancer and the conformality achieved with proton therapy to deliver an abbreviated course of therapy for low-risk prostate cancer. [1][2][3][4][5][6] All patients required image guidance with fiducial placement and magnetic resonance imaging registration. The rationale of this image guidance approach for proton therapy has been reviewed previously.…”

Dose specification in External Beam Radiotherapy for CyberKnife and VMAT techniques applied to a case of prostate cancer

“…In order to assess the differences between doses to the CTV (Clinical Target Volume) and PTV, in the form of dose sets for both techniques, the exported differential DVH files were compared by the t-test for independent samples using STATISTICA v. 10 software; statistical significance being taken as ≤ 0.05. In-house RPIWin software was also used to calculate the RPI coefficient [16] for determining the differences in dose distribution between both techniques; this being achieved by using cumulative DVH's for both techniques. Finally, bioequivalent doses (Diso2Gy) were calculated for both treatment methods, and based on the mean dose they were normalised to the 2Gy fraction using a linear-quadratic model (LQ).…”