In this chapter, we present a comparative study of nanowire arrays for the purpose of transmitting electromagnetic energy to long distances with minimum loss. Silver nanowires at an infrared frequency are considered as a case study, using an accurate simulation environment based on the surface-integral equations and the multilevel fast multipole algorithm (MLFMA). Reliable numerical results are obtained by considering arrays as three-dimensional structures with finite sizes in all dimensions. Nanowires with different cross sections are compared in alternative array configurations to assess and compare their transmission properties. While there are no significantly varying performances for the arrays of few elements, large discrepancies occur as the number of nanowires increases. We show that arrays involving nanowires with hexagonal cross sections in hexagonal arrangements can provide significantly better power transmissions in comparison to others. We also present the superiority of a particular case, where the nanowires and gaps between them, both with hexagonal cross sections, are equally distributed, leading to a honeycomb structure. This type of structures demonstrates high-quality transmissions that can be useful in diverse application areas, such as optical coupling, subwavelength imaging, and energy harvesting.