Integral valorisation of tomato by-products towards bioactive compounds recovery: Human health benefits

Damasceno, Marta Maria Coelho; Rodrigues, António Teixeira; Teixeira, J. A.; Pintado, Manuela

doi:10.1016/j.foodchem.2022.135319

Cited by 39 publications

(27 citation statements)

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“…SFE is an extraction technique that reduces the toxic solvents used during the process and can generate a solvent-free extract at moderately high selectivity and yield temperatures [ 11 ]. Although it is a non-inflammable and non-toxic method, its non-polar nature demands the use of a stabiliser and a cosolvent, and carotenoid degradation and/or isomerization can occur [ 40 , 41 ].…”

Section: Bioaccessibility and Bioavailability Of Carotenoidsmentioning

confidence: 99%

“…More recently, Coelho et al [ 47 ] proposed OH, which consists of the use of an electric current that passes across a conductor matrix (e.g., food) to generate heat from the electrical resistance of the matrix. This methodology is more advantageous than the ones mentioned before since it allows the extraction of bioactive compounds such as carotenoids and polyphenols from their matrices only using ethanol:water as a solvent [ 45 , 47 ], and the application of a low temperature prevents thermal losses [ 11 ].…”

Section: Bioaccessibility and Bioavailability Of Carotenoidsmentioning

confidence: 99%

“… Advantages and limitations of using Ohmic heating (OH) in the extraction of bioactive compounds. Adapted from [ 11 ]. …”

Section: Figurementioning

confidence: 99%

“…If they are pure hydrocarbons, they can be classified as carotenes such as alpha(α)-carotene, beta(β)-carotene, and lycopene [ 8 ]. Xanthophylls are carotenoids with oxygenated derivatives on their terminal rings [ 8 ], with complex xanthophylls containing oxygen substituents, aldehyde groups, epoxide groups and oxo/keto groups [ 11 ]. Zeaxanthin, lutein, canthaxanthin, violaxanthin and neoxanthin are examples of complex xanthophylls.…”

Section: Introductionmentioning

confidence: 99%

“…These antioxidant phytochemicals are also important dietary sources of vitamin A and protect cells and tissues from oxidative damage, interacting with other antioxidants [ 11 , 25 ]. So far, only 50 carotenoids are known to have provitamin A activity [ 12 ], with α-carotene, β-carotene, gamma(γ)-carotene, and β-cryptoxanthin being the most important precursors of vitamin A in humans [ 12 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Carotenoids Diet: Digestion, Gut Microbiota Modulation, and Inflammatory Diseases

et al. 2023

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Several epidemiologic studies have found that consuming fruits and vegetables lowers the risk of getting a variety of chronic illnesses, including several types of cancers, cardiovascular diseases (CVDs), and bowel diseases. Although there is still debate over the bioactive components, various secondary plant metabolites have been linked to these positive health benefits. Many of these features have recently been connected to carotenoids and their metabolites’ effects on intracellular signalling cascades, which influence gene expression and protein translation. Carotenoids are the most prevalent lipid-soluble phytochemicals in the human diet, are found in micromolar amounts in human serum, and are very susceptible to multiple oxidation and isomerisation reactions. The gastrointestinal delivery system, digestion processes, stability, and functionality of carotenoids, as well as their impact on the gut microbiota and how carotenoids may be effective modulators of oxidative stress and inflammatory pathways, are still lacking research advances. Although several pathways involved in carotenoids’ bioactivity have been identified, future studies should focus on the carotenoids’ relationships, related metabolites, and their effects on transcription factors and metabolism.

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Section: Bioaccessibility and Bioavailability Of Carotenoidsmentioning

confidence: 99%