2017
DOI: 10.1016/j.atmosenv.2017.08.003
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Integrated analysis of numerical weather prediction and computational fluid dynamics for estimating cross-ventilation effects on inhaled air quality inside a factory

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Cited by 19 publications
(5 citation statements)
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“…These experimental approaches are, however, limited by ethical issues and animal protection. From this perspective, a computer simulation model (ie, in silico model) presents itself as an alternative and complementary approach that may strongly aid in understanding of the contaminant transport mechanisms in the respiratory system and the absorption of contaminants onto skin 28‐30 . In the assessment of inhalation exposure risk, computational fluid dynamics (CFD) and physiologically based pharmacokinetic (PBPK) models have been applied to realistic respiratory tract models to predict inhalation dosimetry 31‐42 .…”
Section: Introductionmentioning
confidence: 99%
“…These experimental approaches are, however, limited by ethical issues and animal protection. From this perspective, a computer simulation model (ie, in silico model) presents itself as an alternative and complementary approach that may strongly aid in understanding of the contaminant transport mechanisms in the respiratory system and the absorption of contaminants onto skin 28‐30 . In the assessment of inhalation exposure risk, computational fluid dynamics (CFD) and physiologically based pharmacokinetic (PBPK) models have been applied to realistic respiratory tract models to predict inhalation dosimetry 31‐42 .…”
Section: Introductionmentioning
confidence: 99%
“…Urban scale models utilizing Computational Fluid Dynamic (CFD) simulations have also been proposed. However, their computational complexity limits their applicability to a wide area [14,15,22,24]. Besides these model-driven approaches, data-driven methods have become popular due to the increased use of monitoring stations, including traditional fixed networks, denser networks of low-cost fixed sensors, and low-cost mobile devices.…”
Section: Related Workmentioning
confidence: 99%
“…Highly heterogeneous airflow and scalar distributions, such as those of chemical compounds, in an enclosed space are generally formed by a complex and nonlinear fluid motion 1‐6 . In particular, in a factory or chemical plant with a large indoor volume, the tendency toward heterogeneity associated with incomplete mixing is accentuated 7‐10 . In addition to the transient and heterogeneous airflow pattern, another important factor in the formation of this non‐uniform scalar concentration distribution is the heterogeneity of the emission source of the scalar.…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3][4][5][6] In particular, in a factory or chemical plant with a large indoor volume, the tendency toward heterogeneity associated with incomplete mixing is accentuated. [7][8][9][10] In addition to the transient and heterogeneous airflow pattern, another important factor in the formation of this non-uniform scalar concentration distribution is the heterogeneity of the emission source of the scalar. Discussions of exposure concentrations of hazardous chemicals and the corresponding health risks to indoor residents must be premised on an accurate understanding of airflow patterns and the location of emission sources of the target chemical compound.…”
mentioning
confidence: 99%