Integrated approaches for reducing sample size for measurements of trace elemental impurities in plutonium by ICP-OES and ICP-MS

A Review on the recent approaches for the analysis of Elemental impurities by ICP-based techniques

“…The simple workflow minimises the steps taken to carry out a mission, leaving more time for analysts to focus on other activities. The ICP-OES system is used to determine the presence of minute quantity impurities and gallium content in plutonium metals with enhanced accuracy, precision and detection limits 24 . The ICP-OES instrument is also appropriate for the dilute-and-shoot technique to determine different elemental impurities in pharmaceutical liquid samples.To correct the matrix results, however, customised calibration methods are needed, enabling the dilute-andshoot technique to be applied to 10-hold diluted samples and making the elemental impurity analysis of liquid drugs feasible by ICP-OES.…”

Evaluation and Specifications for In-Line Uranium Separations Using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) Detection for Trace Elemental Analysis

“…5,8,9 Trace elemental analysis by ICP-MS can be performed by diluting the sample such that the matrix (e.g., U or Pu) is at low concentrations, typically 100-500 mg g -1 , to provide accurate determinations of the impurities assuming there are no elements of interest which would possess matrix-based isobaric interferences. [10][11][12][13][14] For elements that are commonly hidden by isobaric interferences such as 24 Mg ( 12 C 12 C), 39 K ( 38 Ar 1 H), 40 Ca ( 40 Ar), and 56 Fe ( 40 Ar 16 O), ICP-OES is traditionally utilized. Unfortunately, for the ICP-OES measurement, the electron-rich U/Pu matrix must be removed before analysis to minimize the spectral interferences associated with the measurement.…”