The Okrika Stretch of Bonny River, Nigeria, has long been a vital ecological and economic resource for the surrounding communities. However, increasing industrialization and anthropogenic activities have raised concerns about the potential pollution of this precious aquatic ecosystem. This study delves into the assessment of environmental trace metal concentrations, specifically Lead (Pb), Nickel (Ni), Zinc (Zn), Copper (Cu), and Iron (Fe), as pollution indicators in various components of the Okrika Stretch. The research scrutinizes water, sediment, oyster, and periwinkle samples, utilizing cutting-edge analytical techniques to measure trace metal levels. Sampling was carried out at five distinct locations, including a control site situated outside the presumed affected area, for both dry and wet seasons throughout the year. Following collection, the samples of water, sediment, oyster, and periwinkle underwent digestion and subsequent analysis using the Bulk Scientific Model 200A Atomic Absorption Spectrophotometer (AAS). Our findings reveal a complex interplay of trace metal concentrations across different environmental components. The water samples exhibit varying levels of these metals, reflecting the dynamic nature of riverine systems. Sediment analysis identifies hotspots of metal accumulation, potentially posing risks to aquatic life. Oysters and periwinkles, as vital components of the food web, accumulate trace metals at different rates, providing insights into potential human health implications. This research not only sheds light on the current state of pollution within the Okrika Stretch but also underscores the importance of continued monitoring and mitigation efforts. The results call for a comprehensive environmental management strategy to safeguard the ecological and economic sustainability of the Bonny River region. By addressing the complexities of trace metal pollution, this study contributes to the broader discourse on safeguarding our invaluable aquatic ecosystems worldwide.