“…The process constitutes the direct land application of in natura vinasse into sugarcane fields to recycle nutrients and water to the crop (Dias et al, emission of greenhouse gases, such as nitrogen oxides and methane (Oliveira et al, 2013). Anaerobic digestion (AD), or biodigestion, is considered one of the most suitable technological approaches to the management of vinasse in biorefineries because both environmental adequacy and bioenergy recovery could be achieved through the controlled conversion of organic matter into biogas without significant losses in the fertilizing potential of vinasse (Fuess and Garcia, 2015;Moraes et al, 2015;Ryan et al, 2009). A large number of studies have investigated the application of AD to sugarcane vinasse (Bories et al, 1988;Costa et al, 1986;Craveiro et al, 1986;Ferraz et al, 2016;Fuess et al, 2017;Kumar et al, 2007;Siqueira et al, 2013;Souza et al, 1992) in an effort to optimize treatment performances by applying different reactor configurations and operating strategies.…”