Integrated photo-inspired antibacterial polyvinyl alcohol/carboxymethyl cellulose hydrogel dressings for pH real-time monitoring and accelerated wound healing

Yang, Yuanyuan; Zhang, Chong; Gong, Mali; Zhan, Yuan; Yu, Zhenkun; Shen, Chen; Zhang, Yuhong; Li, Yu; Chen, Zhaoxia

doi:10.1016/j.ijbiomac.2023.124123

Cited by 17 publications

(4 citation statements)

References 59 publications

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“…Consequently, researchers have proposed the development of multifunctional hydrogel-based dressings to enable comprehensive monitoring of various parameters in wound healing, including pH levels, pressure, infection status, temperature, and glucose levels. 303–307 A novel method has been developed for the in situ biosynthesis of functional conjugated polymers within artificial hydrogels, utilizing the biological microenvironment. This approach allowed for the real-time monitoring of wound infection and the inhibition of bacteria.…”

Section: Application Of Hydrogel-based Dressings In Different Types O...mentioning

confidence: 99%

Hydrogel-based dressings designed to facilitate wound healing

Zhang,

Liu,

Cheng

et al. 2024

Mater. Adv.

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Section: Application Of Hydrogel-based Dressings In Different Types O...mentioning

confidence: 99%

Hydrogel-based dressings designed to facilitate wound healing

Zhang,

Liu,

Cheng

et al. 2024

Mater. Adv.

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“…The integrated light-induced antimicrobial system offers a creative way to track wound healing in real time and quickly diagnose it, with great potential for clinical use. [250]…”

Section: Antibacterial Therapymentioning

confidence: 99%

Photo‐Controllable Smart Hydrogels for Biomedical Application: A Review

Zhao,

Ran,

Lee

et al. 2023

Small Methods

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Nowadays, smart hydrogels are being widely studied by researchers because of their advantages such as simple preparation, stable performance, response to external stimuli, and easy control of response behavior. Photo‐controllable smart hydrogels (PCHs) are a class of responsive hydrogels whose physical and chemical properties can be changed when stimulated by light at specific wavelengths. Since the light source is safe, clean, simple to operate, and easy to control, PCHs have broad application prospects in the biomedical field. Therefore, this review timely summarizes the latest progress in the PCHs field, with an emphasis on the design principles of typical PCHs and their multiple biomedical applications in tissue regeneration, tumor therapy, antibacterial therapy, diseases diagnosis and monitoring, etc. Meanwhile, the challenges and perspectives of widespread practical implementation of PCHs are presented in biomedical applications. This study hopes that PCHs will flourish in the biomedical field and this review will provide useful information for interested researchers.

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“… Antibacterial photo-inspired WD, based on CMC as the “network backbone” hydrogel, polyvinyl alcohol (PVA) with iodophor (KI-I 2 ) as the antimicrobial hydrogel, and a fluorescent material (carbon quantum dots) as the doping agent. This functional material releases desired doses of an antibacterial agent (I 2 ), and provides real-time information on the wound healing process, based on hydrogel color responsiveness to wound pH changes in UV and visible light [ 81 ]. Multilayer microneedles, based on PVA and CMC for the transdermal delivery of nicotinamide mononucleotide (antiaging agent).…”

Section: Natural Products From Plants Used In Medical Devicesmentioning

confidence: 99%

From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds

Isopencu,

Covaliu-Mierlă,

Deleanu

2023

Plants

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Transdermal delivery devices and wound dressing materials are constantly improved and upgraded with the aim of enhancing their beneficial effects, biocompatibility, biodegradability, and cost effectiveness. Therefore, researchers in the field have shown an increasing interest in using natural compounds as constituents for such systems. Plants, as an important source of so-called “natural products” with an enormous variety and structural diversity that still exceeds the capacity of present-day sciences to define or even discover them, have been part of medicine since ancient times. However, their benefits are just at the beginning of being fully exploited in modern dermal and transdermal delivery systems. Thus, plant-based primary compounds, with or without biological activity, contained in gums and mucilages, traditionally used as gelling and texturing agents in the food industry, are now being explored as valuable and cost-effective natural components in the biomedical field. Their biodegradability, biocompatibility, and non-toxicity compensate for local availability and compositional variations. Also, secondary metabolites, classified based on their chemical structure, are being intensively investigated for their wide pharmacological and toxicological effects. Their impact on medicine is highlighted in detail through the most recent reported studies. Innovative isolation and purification techniques, new drug delivery devices and systems, and advanced evaluation procedures are presented.

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Integrated photo-inspired antibacterial polyvinyl alcohol/carboxymethyl cellulose hydrogel dressings for pH real-time monitoring and accelerated wound healing

Cited by 17 publications

References 59 publications

Hydrogel-based dressings designed to facilitate wound healing

Hydrogel-based dressings designed to facilitate wound healing

Photo‐Controllable Smart Hydrogels for Biomedical Application: A Review

From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds

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