“…Additionally, several authors have sought the sustainable synthesis of processing schemes in retrofit scenarios, even if they use heuristic approaches based on path flow decomposition and indicator-based assessment [33,34,35,36,37]. Besides, the use of dynamic performance models in allocation problems has received a strong impulse in the last two decades in the context of shortterm scheduling, even though these contributions do not cover other synthesis and design decisions, such as the selection of process technologies, chemicals, or equipment sizing, among others [38,39,40,41,42].…”