Integrating Interactive Web-Based Technology to Assess Adherence and Clinical Outcomes in Pediatric Sickle Cell Disease

Crosby, Lori E.; Barach, Ilana; McGrady, Meghan E.; Kalinyak, Karen; Eastin, Adryan R.; Mitchell, Monica J.

doi:10.1155/2012/492428

Cited by 39 publications

(63 citation statements)

References 40 publications

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“…Facilitators of adherence include: health benefits of therapy, social support systems, medication reminders and positive clinic experiences [33]. In addition to health education, the following methods have been shown to improve compliance with treatment: (1) multimedia communication for hospitalized patients with their teachers and work colleagues, (2) integration of interactive web-based technology to assess adherence to therapy, (3) electronic DOT, and (4) coaching very young children for swallowing hydroxyurea capsules [33][34][35][36][37].…”

Section: Discussionmentioning

confidence: 99%

Adherence to Hydroxyurea Therapy in Patients with Sickle Cell Disease at King Khalid University Hospital in Riyadh

Hn¹,

Ak²,

Am³

et al. 2014

J Blood Disord Transfus

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Section: Discussionmentioning

confidence: 99%

Adherence to Hydroxyurea Therapy in Patients with Sickle Cell Disease at King Khalid University Hospital in Riyadh

Hn¹,

Ak²,

Am³

et al. 2014

J Blood Disord Transfus

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“…A similar approach, to test medication adherence, was successfully introduced by Crosby et al [16] in 43 children and adolescents (age range 6-21) with sickle cell disease (SCD) showing 90% satisfaction with patients. This data highlights the potential to integrate smart web-based technology into paediatric clinical care.…”

Section: Adherence To Prescribed Medicationsmentioning

confidence: 99%

Harnessing interactive technologies to improve health outcomes in juvenile idiopathic arthritis

et al. 2017

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Background: Children and adolescents with Juvenile Idiopathic Arthritis (JIA) typically have reduced physical activity level and impaired aerobic and anaerobic exercise capacity when compared to their non-JIA counterparts. Low intensity exercise regimens appear to be safe in children with JIA and may results in improvements in overall physical function. Poor adherence to paediatric rheumatology treatment may lead to negative clinical outcomes and possibly increased disease activity. This includes symptoms such as pain, fatigue, quality of life, longer term outcomes including joint damage, as well as increase of healthcare associated costs. Low adherence to medications such as methotrexate and biological-drugs remains a significant issue for paediatric rheumatologists, with alarming reports that less than half of the children with JIA are compliant to drug-therapy. Main body: The recent advances in interactive technology resulting in a variety of wearable user-friendly smart devices may become a key solution to address important questions in JIA clinical management. Fully understanding the impact that arthritis and treatment complications have upon individual children and their families has long been a challenge for clinicians. Modern interactive technologies can be customised and accessed directly in the hands or wrists of children with JIA. These secured networks could be accessible 'live' at anytime and anywhere by the child, parents and clinicians. Multidisciplinary teams in paediatric rheumatology may benefit from adopting these technologies to better understand domains such as patient biological parameters, symptoms progression, adherence to drug-therapy, quality of life, and participation in physical activities. Most importantly the use of smart devices technologies may also facilitate more timely clinical decisions, improve self-management and parents awareness in the progression of their child's disease. Paediatric rheumatology research could also benefit from the use of these smart devices, as they would allow real-time access to meaningful data to thoroughly understand the disease-patterns of JIA, such as pain and physical activity outcomes. Data collection that typically occurs once every 1 or 3 months in the clinical setting could instead be gathered every week, day, minute or virtually live online. Arguably, few limitations in wearing such interactive technologies still exist and require further developments. Conclusion: Finally, by embracing and adapting these new and now highly accessible interactive technologies, clinical management and research in paediatric rheumatology may be greatly advanced.

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“…age, sex, demographic variables, type of disease), the type of treatment or behavior evaluated (the majority of data is on pharmacoadherence), the measure used to assess adherence and the definition of nonadherence. To highlight the importance of defining nonadherence, as discussed above, when adherence is defined as perfect adherence, more than 70% of certain AYA [50] or adult [39] hematology populations may be nonadherent according to self-report.…”

Section: Adolescents and Young Adultsmentioning

confidence: 99%

Adherence-Related Issues in Adolescents and Young Adults with Hematological Disorders

Leader

Raanani²

2014

Acta Haematol

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Nonadherence to medical recommendations is a widespread problem well documented in a multitude of clinical settings. Nonadherence may adversely affect clinical outcomes such as survival and quality of life and increase health-care-related costs. An understanding of the factors driving nonadherence is key to developing effective adherence-enhancing interventions (AEIs). There are ongoing attempts in contemporary adherence research to better define the various components of adherence, to find optimal measures of adherence and correlations with clinical outcomes, and to create a classification system for AEIs. Nonadherence is also widely prevalent among adolescents and young adults (AYAs) with chronic hematological diseases, affecting up to 50% of patients and increasing with age. Combined use of objective (i.e. electronic monitoring, EM) and subjective (i.e. self-report) measures of adherence may be the preferred approach to assess adherence. The unique physical, social and emotional aspects of the AYA life stage are closely related to intricate causes of nonadherence in AYAs such as problems in transition to adult care. Until proven otherwise, the empirical target in AYAs with hematological disorders should be perfect adherence. Multilevel AEIs, EM feedback and behavioral interventions are among the most effective types of AEIs. Despite the magnitude of the problem, only a handful of AEIs have been evaluated among AYAs with hematological disorders. Thus, this is a field with unmet needs warranting high-quality trials using standardized and well-specified assessment methods and interventions. This review discusses the prevalence, definition, causes and clinical implications of nonadherence among AYAs with hematological disorders, along with strategies to measure and improve adherence.

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Integrating Interactive Web-Based Technology to Assess Adherence and Clinical Outcomes in Pediatric Sickle Cell Disease

Cited by 39 publications

References 40 publications

Adherence to Hydroxyurea Therapy in Patients with Sickle Cell Disease at King Khalid University Hospital in Riyadh

Adherence to Hydroxyurea Therapy in Patients with Sickle Cell Disease at King Khalid University Hospital in Riyadh

Harnessing interactive technologies to improve health outcomes in juvenile idiopathic arthritis

Adherence-Related Issues in Adolescents and Young Adults with Hematological Disorders

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