ABSTRACT. Mountain ecosystems provide a broad range of ecosystem services (ES). Trade-offs between different ES are an important aspect in the assessment of future sustainable land-use. Management of ES in mountain regions must confront the challenges of spatial and temporal heterogeneity, and interaction with structural changes in agriculture and forestry. Using a social-ecological modeling framework, we assess the relationships between forest and agricultural ES in a mountain region in Switzerland. Based on the concept of jointness in production, we evaluated trade-offs and synergies among food provision, biodiversity conservation, carbon sequestration, and protection against natural hazards. Results show that increasing the provision of a focal ES in a mountain region may result in alternating trade-offs and synergies, depending on the interaction of economic and technological interdependencies. Thus, management schemes aiming to increase the provision of one focal ES have to consider not only the technological or biological nature of interrelationships, but also the economic interdependencies among different ES. Trade-offs and synergies from these interactions strongly depend on the underlying structural and environmental conditions driven by socioeconomic and climatic developments.