The novel coronavirus, COVID-19, proliferates as a contagious psychological threat just like the physical disease itself. Due to the growing death toll and constant coverage this pandemic gets, it is likely to activate mortality awareness, to greater or lesser extents, depending on a variety of situational factors. Using terror management theory and the terror management health model, we outline reactions to the pandemic that consist of proximal defences aimed at reducing perceived vulnerability to (as well as denial of) the threat, and distal defences bound by ideological frameworks from which symbolic meaning can be derived. We provide predictions and recommendations for shifting reactions to this pandemic towards behaviours that decrease, rather than increase, the spread of the virus. We conclude by considering the benefits of shifting towards collective mindsets to more effectively combat COVID-19 and to better prepare for the next inevitable pandemic.COVID-19, the disease caused by the virus SARS-CoV-2, was declared a pandemic by the World Health Organization Director-General on 11 March 2020. In countries most severely impacted by the disease, case fatality rates are thought to be as high as 15% (e.g., Belgium, 15.2%; 'Mortality Analyses', 2020). COVID-19 poses both a physical threat, due to its contagiousness, and a psychological threat through the fear it provokes (a phenomenon referred to as 'coupled contagion' by Epstein, 2020;Epstein et al., 2008). Terror management theory (TMT; Greenberg, Pyszczynski, & Solomon, 1986), which offers predictions for how people behave in response to fear associated with mortality, helps shed light on this unprecedented existential threat. In this paper, we rely on an extension of TMT, the terror management health model (TMHM; Goldenberg & Arndt, 2008), to investigate and make predictions about this pandemic, and provide recommendations for encouraging behaviour to slow the spread of COVID-19 and other potential pandemic diseases in the future.