Integration of Graphene on AlN Based High Frequency Resonators and Their Functionalization for Biosensing

Abstract

Abstract:We present the successful integration of graphene on top of AlN-based solidly mounted resonators (SMRs), using a low temperature CVD process and Ni layers as catalyst. We develop a protocol to functionalize the surface of the resonators that starts with a low damage O2 radical plasma treatment of the surface of the devices that introduces a controlled density of defects on the graphene. Then, EDC/NHS chemistry is used to covalently bond streptavidin molecules to the surface of the sensors. Finally, the functionalised biosensors are assessed by analysing their response to biotinylated antibodies.

Graphene Nanomaterials-Based Radio-Frequency/Microwave Biosensors for Biomaterials Detection

“…As shown in Table 2, the studies of graphene nanomaterials as RF/microwave devices and circuits such as resonators, transmission lines, antennas, and interconnects have been carried out. In particular, the graphene-based resonator has been widely examined on the feasibility as an RF/microwave biosensing device because of its easy characterization and fast discrimination of the biomolecular detection [69,70]. In the case of GO, this has been frequently used as a type of biological matrix at the gap between RF/microwave electrodes or conventional devices and circuits, e.g., interdigitated capacitor and transmission line, and so on [71,72].…”