Integration of IFAST-based nucleic acid extraction and LAMP for on-chip rapid detection of Agroathelia rolfsii in soil

“Three-in-One” Plasmonic Au@PtOs Nanocluster Driven Lateral Flow Assay for Multimodal Cancer Exosome Biosensing

“…Lateral flow assay (LFA) has attracted wide attention in the diagnostic field due to the advantages of rapidity, low cost, and ease-of-use. − These years, LFA has been applied in various fields including environmental pollutant analysis, , food safety surveillance, , and particularly point-of-care disease diagnosis. − However, traditional Au nanoparticles (Au NPs) based LFA can only provide limited sensitivity and quantitative ability; therefore, developing novel strategies to improve the sensitivity and quantitative capability of LFAs was urgently required. , …”

Sample-to-Answer Detection of SARS-CoV-2 Viremia Using Thermally Responsive Alkane Partitions

“…Generally, these implementations use oil to separate aqueous reagent layers; paramagnetic beads can be pulled through the oil layers from one reagent to the next without disturbing the partitions. Multiple reports have demonstrated integration of some of the sample preparation steps with NAATs using microfluidic channels. − However, the manufacturing of microfluidic chips with integrated oil partitions may be challenging. In an alternative approach, Shin et al have demonstrated the use of multiwell cassettes with an oil layer covering the wells to maintain partitioning; an external magnet transfers beads from each well to the next to perform sample preparation and qPCR. , Trick et al incorporated a filter onto the cassette to enable compatibility with whole blood samples …”