Integration of liquid chromatography mass spectrometry with a heavy peptide response curve accurately measures unprocessed C-terminal lysine during peptide mapping analysis of therapeutic antibodies in a single run

Greer, Tyler; Johnson, Reid O’Brien; Cejkov, Milos; Zheng, Xiaojing; Li, Ning

doi:10.1016/j.jpba.2021.113963

Journal of Pharmaceutical and Biomedical Analysis

2021

DOI: 10.1016/j.jpba.2021.113963

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Integration of liquid chromatography mass spectrometry with a heavy peptide response curve accurately measures unprocessed C-terminal lysine during peptide mapping analysis of therapeutic antibodies in a single run

Tyler Greer

Reid O’Brien Johnson

Milos Cejkov

et al.

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Integration of liquid chromatography mass spectrometry with a heavy peptide response curve accurately measures unprocessed C-terminal lysine during peptide mapping analysis of therapeutic antibodies in a single run

Cited by 1 publication

References 29 publications

High throughput and high confidence sequence variant analysis in therapeutic antibodies using Evosep One liquid chromatography tandem mass spectrometry with synthetic heavy peptides

High throughput and high confidence sequence variant analysis in therapeutic antibodies using Evosep One liquid chromatography tandem mass spectrometry with synthetic heavy peptides

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