2024
DOI: 10.21203/rs.3.rs-3959082/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Integration of Multi-omics Data Revealed the Orphan CpG Islands and Enhancer-dominated Cis-regulatory Network in Glioma

jiawei yao,
Penglei Yao,
Yang Li
et al.

Abstract: Background: The complex transcriptional regulatory network leads to the poor prognosis of glioma. The role of orphan CpG islands (oCGIs) in the transcriptional regulatory network has been overlooked. Establishing a sophisticated transcriptional regulatory system is paramount.Methods: We constructed different cis-regulatory models through mutual information and Bayesian networks. We utilized eleven machine learning algorithms to develop classifiers that could effectively integrate multi-omics datasets. we utili… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 40 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?