Electro-optic modulation (EOM) is an essentially important optical manipulation for on-chip photonics, optical communication and optical sensing. With emerging demands on efficient, broadband electro-optic modulation, the highperformance, integrated electro-optic modulation becomes indispensable. By manipulating phase or amplitude of optical field, optical information will be coded/modulated for communication or modulation. Through advanced micro/ nano fabrication technique, the electro-optics crystal could be cut into the required volume/shape as specific, integrated modulator, waveguide or meta-surface for nano-photonic applications, paving a solid way for the imminent nano-photonic devices. Herein, the basic electro-optics effects, opto-electronic applications, methods of fabrication/integration, and future prospect of lithium niobate crystal are discussed or introduced. Demonstrations of box-sealed EOM, in-fiber EOM and the fabricated lithium niobate waveguides on substrate will be found here.