Abstract-Trajectory-Based Operations is a NextGen initiative that seeks to increase the effective-capacity of the National Airspace System by adding flexibility to the 4-D trajectories as flights traverse airspace. More flexible trajectories can minimize the airlines operating costs (i.e., distance flown), shift the geography of Air Traffic Control (ATC) workload (i.e., sectors used), shift the time-intensity of ATC workload (i.e., flights counts per sector), and reduce congestion in the destination airports.This paper describes the results of an analysis of one day of operations, including domestic and international flights, in the NAS using traditional navigation aid-based airway routes compared to direct, i.e., Great Circle Distance, routes. Apart from the total of 1,608,751 nm (average 24.7 nm per flight) savings in distance flown generated by flying Great Circle Distance Routes, the results show: (i) a redistribution of flights across sectors resulting in a reduction of 3% in the total time the flights in a sector are in excess of the Monitor Alert Parameters for that sector, (ii) a reduction in ATC workload reflected by a 42% drop in the number of flights requiring conflict resolution, (iii) the average ground delay due to the natural limits in the arrival capacity of the OEP-35 airports increases when using direct routes, but the increase is small, (iv) the congestion at the destination airports remains the same. These results indicate the upper bound of benefit opportunities for both ATC and the airlines based on the introduction of flexible routing structures in NextGen, but no improvement for the airports in terms of congestion.