Integrative and Palliative Medicine Synergy: Structures and Solutions

Gentile, Danielle; Blake, Sarah; Greiner, Rebecca; Kneuss, Tiffany; Spencer, Latoya; Yaguda, Susan; Bailey-Dorton, Chasse Margot; Parala-Metz, Armida

doi:10.1089/acm.2019.0398

Cited by 4 publications

(14 citation statements)

References 16 publications

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“…Integrative oncology (IO) and palliative medicine (PM) are effective at reducing the high symptom burden that cancer patients and survivors frequently endure (Gentile et al, 2020). The goal of IO is to "optimize health, quality of life, and clinical outcomes through the use of mind-body practices, natural products, and/or lifestyle alterations in addition to conventional cancer treatments" (Witt et al, 2017).…”

Section: Synergy With Complementary Treatment Modalitiesmentioning

confidence: 99%

Overcoming challenges in cancer treatment: Nano‐enabled photodynamic therapy as a viable solution

Rajan,

Chandran,

Abrahamse

2024

WIREs Nanomed Nanobiotechnol

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Cancer presents a formidable challenge, necessitating innovative therapies that maximize effectiveness while minimizing harm to healthy tissues. Nanotechnology has emerged as a transformative force in cancer treatment, particularly through nano‐enabled photodynamic therapy (NE‐PDT), which leverages precise and targeted interventions. NE‐PDT capitalizes on photosensitizers activated by light to generate reactive oxygen species (ROS) that initiate apoptotic pathways in cancer cells. Nanoparticle enhancements optimize this process, improving drug delivery, selectivity, and ROS production within tumors. This review dissects NE‐PDT's mechanistic framework, showcasing its potential to harness apoptosis as a potent tool in cancer therapy. Furthermore, the review explores the synergy between NE‐PDT and complementary treatments like chemotherapy, immunotherapy, and targeted therapies, highlighting the potential to amplify apoptotic responses, enhance immune recognition of cancer cells, and inhibit resistance mechanisms. Preclinical and clinical advancements in NE‐PDT demonstrate its efficacy across various cancer types. Challenges in translating NE‐PDT into clinical practice are also addressed, emphasizing the need for optimizing nanoparticle design, refining dosimetry, and ensuring long‐term safety. Ultimately, NE‐PDT represents a promising approach in cancer therapy, utilizing the intricate mechanisms of apoptosis to address therapeutic hurdles. The review underscores the importance of understanding the interplay between nanoparticles, ROS generation, and apoptotic pathways, contributing to a deeper comprehension of cancer biology and novel therapeutic strategies. As interdisciplinary collaborations continue to thrive, NE‐PDT offers hope for effective and targeted cancer interventions, where apoptosis manipulation becomes central to conquering cancer.This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease

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Section: Synergy With Complementary Treatment Modalitiesmentioning

confidence: 99%

Overcoming challenges in cancer treatment: Nano‐enabled photodynamic therapy as a viable solution

Rajan,

Chandran,

Abrahamse

2024

WIREs Nanomed Nanobiotechnol

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“…Diuretics: Diuretics, often known as water pills, function to eliminate surplus fluid from the body, thereby alleviating the burden on the renal system [14]. Loop diuretics, such as furosemide, are frequently utilized to manage edema linked to renal failure.…”

Section: Conventional Treatment Modalities For Renal Conditionsmentioning

confidence: 99%

“…The utilization of this approach has the potential to enable patients to actively participate in making informed decisions regarding their healthcare, thereby cultivating a sense of autonomy and responsibility in managing their health trajectories. Moreover, combining several components can enhance treatment adherence and ultimately improve outcomes [14].…”

Section: Introductionmentioning

confidence: 99%

Integrative Medicine Approaches: Bridging the Gap Between Conventional and Renal Complementary Therapies

Kalariya,

Kumar,

Ullah

et al. 2023

Cureus

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The global incidence of renal disorders is on the rise, demanding the implementation of novel and comprehensive strategies for patient care. The present study demonstrates the significance of renal health, offering a comprehensive comprehension of renal physiology and the escalating load of renal illnesses. The relevance of controlling renal illnesses is underscored by a thorough examination of conventional treatments, which encompass pharmaceutical interventions, dialysis, and transplantation. Subsequently, the story redirects its attention towards complementary therapies, classifying them into several categories, such as herbal medicine, acupuncture, dietary supplements, and mind-body activities, among various others. This paper presents a comprehensive examination of the available information, providing a critical study of the effectiveness and safety of alternative therapies in renal care. This study focuses on the central idea of integrative medicine, distinguished by its patient-centered and holistic approach and its seamless integration of conventional and complementary therapies. This study examines several integrative care models, using case studies to illustrate successful integrative approaches that have enhanced patient outcomes. The review thoroughly examines the current body of literature on integrative renal care, including meta-analyses, systematic reviews, and notable research discoveries. This study highlights the need for further research to address knowledge gaps and explore areas that require additional examination. These findings emphasize the importance of future research endeavors in this crucial sector. In addition, the paper thoroughly examines the safety issues and regulatory factors pertaining to complementary therapies, underscoring the importance of making educated decisions and maintaining diligent monitoring to safeguard patients' well-being. Integrating patient perspectives, experiences, and shared decision-making is essential to the integrated healthcare process, promoting a collaborative and patient-centered approach. The study culminates by providing a concise overview of the primary discoveries and delineating the ramifications of implementing therapeutic procedures. This statement underscores the considerable potential of integrative medicine in augmenting renal care, ultimately leading to enhanced patient outcomes and an improved overall quality of life for persons with renal diseases. Also, this literature review provides a thorough and knowledgeable examination of the incorporation of conventional and complementary therapies in the context of renal health. It gives valuable perspectives for healthcare practitioners, researchers, and policymakers interested in enhancing care strategies for individuals with renal conditions.

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“…Este es un artículo open access bajo la licencia CC BY-NC-ND (http://creativecommons.org/licenses/by-nc-nd/4.0/). el concepto de medicina integrativa, nos conduce a los cuidados paliativos integrativos como una mejor herramienta para el tratamiento de los enfermos de cáncer en cualquiera de las etapas 6,7 .…”

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Oncología integradora y atención centrada en el paciente: ¿la cirugía paliativa tiene algún papel en estos dos conceptos?

Miranda-Aguirre¹

2022

GAMO

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Integrative and Palliative Medicine Synergy: Structures and Solutions

Cited by 4 publications

References 16 publications

Overcoming challenges in cancer treatment: Nano‐enabled photodynamic therapy as a viable solution

Overcoming challenges in cancer treatment: Nano‐enabled photodynamic therapy as a viable solution

Integrative Medicine Approaches: Bridging the Gap Between Conventional and Renal Complementary Therapies

Oncología integradora y atención centrada en el paciente: ¿la cirugía paliativa tiene algún papel en estos dos conceptos?

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