Integrative considerations during the COVID-19 pandemic

Alschuler, Lise; Weil, Andrew; Horwitz, Randy; Stamets, Paul; Chiasson, Ann Marie; Crocker, Robert; Maizes, Victoria

doi:10.1016/j.explore.2020.03.007

Cited by 60 publications

(75 citation statements)

References 47 publications

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“…In addition to the well‐known personal hygiene and preventive measures against the new coronavirus, thalassaemia patients can also follow some simple recommendations regarding their lifestyle and nutrition that strengthen their immune system and could better prepare them for the ongoing pandemic 34,35 …”

Section: Lifestyle and Nutritional Considerationsmentioning

confidence: 99%

COVID‐19 and thalassaemia: A position statement of the Thalassaemia International Federation

Farmakis

Giakoumis

Cannon³

et al. 2020

European J of Haematology

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Objectives Many patients with haemoglobinopathies, including thalassaemia and sickle cell disease, are at increased risk of developing severe complications from the coronavirus disease 2019 (COVID‐19). Although epidemiologic evidence concerning the novel coronavirus (SARS‐CoV‐2) infection in these patients is currently lacking, the COVID‐19 pandemic represents a significant challenge for haemoglobinopathy patients, their families and their attending physicians. Methods The present statement summarizes the key challenges concerning the management of haemoglobinopathies, with particular focus on patients with either transfusion‐dependent or non‐transfusion‐dependent thalassaemia, identifies the gaps in knowledge and suggests measures and strategies to deal with the pandemic, based on available evidence and expert opinions. Key areas covered include patients’ risk level, adaptation of haemoglobinopathy care, safety of blood transfusions, blood supply challenges, and lifestyle and nutritional considerations. Conclusions The proposed measures and strategies may be useful as a blueprint for other disorders which require regular hospital visits, as well as for the timely adaptation of patient care during similar future pandemics.

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Section: Lifestyle and Nutritional Considerationsmentioning

confidence: 99%

COVID‐19 and thalassaemia: A position statement of the Thalassaemia International Federation

Farmakis

Giakoumis

Cannon³

et al. 2020

European J of Haematology

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“…31,37 Specifically, in confirmed COVID-19 cases, available studies have demonstrated that sleep deprivation tends to increase the CXCL9 levels in the patients-CXCL9 is a substance which increases lymphocytic infiltration and is also implicated in the activation of proinflammatory NLRP3 inflammasome. 11 40 and increase substance misuse. 41…”

Section: Sleepmentioning

confidence: 99%

“…17,53 The hormone that is usually released in response to chronic stress, cortisol, has been shown to have the potential to disrupt immune regulation and is specifically associated with increased proinflammatory cytokines such as IL-6 and suppres-sion of catecholamines and suppressor T-cells. 11,34,54 Chronic stress has also been observed to lower the secondary antibody response to infections. 51 Prolonged stress also tends to result in release of histamines-excess of this can lead to narrowing of the bronchus, and worsen respiratory distress that may result from severe COVID-19.…”

Section: Stressmentioning

confidence: 99%

Strengthening immunity through healthy lifestyle practices: Recommendations for lifestyle interventions in the management of COVID‐19

Monye

Adelowo

2020

Lifestyle Medicine

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Although the practice of strengthening the immune system may not guarantee that people will not contract severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is evidence that suggests that the likelihood and severity of many viral infections can be considerably reduced if appropriate measures are taken to increase the efficacy of the immune response to invading organisms. Evidence-based public health measures to reduce viral spread include-personal isolation, physical distancing, wearing facial masks, frequent hand washing with soap and running water, not touching the face, vaccination, etc. However once infected, recovery relies on host immunity to eradicate the foreign invaders, with symptomatic management, which is the core management strategy in COVID-19 management guidelines. Researchers have observed that severe COVID-19 prevalence and mortality is highest in people with preexisting conditions. Eighty percent of these preexisting diseases are lifestyle related. Also, the science of strengthening the immune system by adopting appropriate lifestyle changes is still evolving, especially among the suspected and confirmed COVID-19 cases. This article briefly highlights the immune response to viral infections including COVID-19 and refers to evidence that healthy lifestyle practices, enshrined as core aspects of lifestyle medicine, can strengthen the immune response to infections. This may improve outcome in COVID-19. We therefore recommend specific evidencebased lifestyle intervention measures that should be considered in the management of COVID-19.

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“…In these Europeans and North American countries, practitioners of integrative, nutritional, naturopathic, Chinese, and other traditional medicine tend to practice philosophically more closely to the Chinese and Indian government perspective. Multiple organizations-the University of Arizona Andrew Weil Center for Integrative Medicine, 7,8 the American Nutrition Association (ANA), 9 and the American Association of Naturopathic Physicians (AANP) 10 among them-responded to COVID-19 by developing resource sites with respectful caveats and then linked professionals and members of the public to potentially useful supportive practices and natural agents cited by the existing suggestive science. These methods might have value in preventing, supporting, complementing, or rehabilitating.…”

mentioning

confidence: 99%

Call to Action: Announcing the Traditional, Complementary and Integrative Health and Medicine COVID-19 Support Registry

Weeks¹

2020

The Journal of Alternative and Complementary Medicine

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Integrative considerations during the COVID-19 pandemic

Cited by 60 publications

References 47 publications

COVID‐19 and thalassaemia: A position statement of the Thalassaemia International Federation

COVID‐19 and thalassaemia: A position statement of the Thalassaemia International Federation

Strengthening immunity through healthy lifestyle practices: Recommendations for lifestyle interventions in the management of COVID‐19

Call to Action: Announcing the Traditional, Complementary and Integrative Health and Medicine COVID-19 Support Registry

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