Objective: I aimed to clarify whether the demographic characteristics of internal medicine residents are related to the training effect of Flipped Teaching based on Video Conference, so as to further improve the teaching management and quality control. Methods: A total of 43 residents who participated in the Flipped Teaching based on Video Conference in April and June were included as the research objects. Online examination was conducted for these residents, and the demographic characteristics of these residents and their examination score were quantitatively analyzed, so as to clarify the correlation between the demographic characteristics of these residents and their examination score. Results: The average score of 43 residents in the online examination was 72.0(64.0-79.0). 40 residents passed the exam, accounting for 93.0%. The bivariate correlations analysis showed that the age, gender, educational background, training batch and training phase of residents were not correlated with the examination score; all P > 0.05. The age, gender, educational background, training batch and training phase of these residents were not correlated with the examination score by single linear regression and multiple linear regression analysis; all P > 0.05. Conclusion: Age, gender, educational background, training batches and training phases of internal medicine residents are not related to the examination score after Flipped Teaching based on Video Conference. Demographic characteristics may not be related to the training effect of residents through preliminary study.