Intelligent computational model for classification of sub-Golgi protein using oversampling and fisher feature selection methods

SubRF_Seq: Identification of Sub-Golgi Protein Types with Random Forest with Partial Sequence Information

“…Data. is experiment uses a new data set created by Ahmad [12]. ere are 87 cis-Golgi protein sequences and 217 trans-Golgi protein sequences in the training set.…”

“…e subcellular position of the Golgi apparatus is different from that of various eukaryotic cells. In most eukaryotic cells, the Golgi apparatus includes cis-Golgi and trans-Golgi [11,12]. Cis-Golgi is mainly composed of vesicles and multiple vesicles form the Golgi pile.…”

Development of Supervised Learning Predictive Models for Highly Non-linear Biological, Biomedical, and General Datasets

“…Nevertheless, such performances can be altered by modifying the network hyperparameters (such as the number of layers or neuron units), often on the cost of overfitting the data. Other works have applied distance-based methods such as KNN (Ahmad et al, 2017), kernel-driven spatial transforms as SVM (Shi et al, 2013;Xiang et al, 2017), and variations of Partial Least Squares PLS (Sun et al, 2017), all after performing a specially tailored data pretreatment. This non-standard pretreatment results in the loss of generality of such approaches.…”

Discrimination of Golgi Proteins Through Efficient Exploitation of Hybrid Feature Spaces Coupled With SMOTE and Ensemble of Support Vector Machine

“…The part in-between cis and trans faces is referred to as medial. Golgi apparatus receives proteins and lipids from endoplasmic reticulum at the cis face, whereas at the trans face, it ships its products towards various destinations [4]. Many inheritable diseases, such as cancer and diabetes, are due to the poor functionality of Golgi apparatus.…”