In this paper, the approach and main advances made in multi-process hybrid production cells (HyProCell) for rapid individualised laser-based production are compiled and discussed, including highlights and achievements. HyProCell constructs automated manufacturing platforms that integrate highly flexible laser-based additive build processes with more conventional yet precise subtractive machining processes and include novel solutions like automatic powder removal system/machines and robot arms in integrated multi-process production cells. The HyProCell approach can either build parts additively from scratch and finish them in a coherent production single line/cell or prepare parts by machining and add laser-based additive features, achieving otherwise impossible shapes. In addition to producing new parts, existing parts can be repaired or improved by adding new details with the HyProCell hybrid concept. The research work includes the design of pilot cell facilities, the development of the, and a new modular architecture including a middleware and integration layer to ensure automation with improved pallet handling systems. Finally, the MES and data management methodologies for future improvements and pilot facility implementation were made.